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A highly sensitive immunoassay using antibody-conjugated spherical mesoporous silica with immobilized enzymes SCIE SCOPUS
- Title
- A highly sensitive immunoassay using antibody-conjugated spherical mesoporous silica with immobilized enzymes
- Date Issued
- 2014-01
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- A highly sensitive immunoassay was developed by using antibody-conjugated spherical mesoporous silica with immobilized enzymes. The higher ratio of enzyme/antibody than conventional ELISA improved both the sensitivity and dynamic range. Especially, the use of spherical mesoporous silica could achieve a limit of detection (LOD) with a sensitivity that is 20 times more than that of ELISA using amorphous silica.
- Keywords
- ELECTROCHEMICAL IMMUNOASSAY; BIOFUEL CELLS; NANOBIOCATALYSIS; ASSAY; DNA
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 50, no. 27, page. 3546 - 3548, 2014-01
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Related Researcher
- 이진우LEE, JIN WOO
- Dept. of Chemical Enginrg