DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jennings, James | - |
dc.contributor.author | Carter, Matthew C. D. | - |
dc.contributor.author | SON, CHANG YUN | - |
dc.contributor.author | Cui, Qiang | - |
dc.contributor.author | Lynn, David, M. | - |
dc.contributor.author | Mahanthappa, Mahesh K. | - |
dc.date.accessioned | 2020-08-25T00:50:16Z | - |
dc.date.available | 2020-08-25T00:50:16Z | - |
dc.date.created | 2020-08-24 | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/104024 | - |
dc.description.abstract | We report the aqueous lyotropic mesophase behaviors of protonated amine-based "lipidoids," a class of synthetic lipid-like molecules that mirrors essential structural features of the multitail bacterial amphiphile lipid A. Small-angle X-ray scattering (SAXS) studies demonstrate that the protonation of the tetra(amine) headgroups of six-tail lipidoids in aqueous HCl, HNO3, H2SO4, and H3PO4 solutions variably drives their self-assembly into lamellar (L-alpha) and inverse micellar (I-II) lyotropic liquid crystals (LLCs), depending on acid identity and concentration, amphiphile tail length, and temperature. Lipidoid assemblies formed in H2SO4(aq) exhibit rare inverse body-centered cubic (BCC) and inverse face-centered cubic (FCC) micellar morphologies, the latter of which unexpectedly coexists with zero mean curvature L-alpha phases. Complementary atomistic molecular dynamics (MD) simulations furnish detailed insights into this unusual self-assembly behavior. The unique aqueous lyotropic mesophase behaviors of ammonium lipidoids originate in their dichotomous ability to adopt both inverse conical and chain-extended molecular conformations depending on the number of counterions and their identity, which lead to coexisting supramolecular assemblies with remarkably different mean interfacial curvatures. | - |
dc.language | English | - |
dc.publisher | American Chemical Society | - |
dc.relation.isPartOf | Langmuir | - |
dc.title | Protonation-Driven Aqueous Lyotropic Self-Assembly of Synthetic Six-Tail Lipidoids | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acs.langmuir.0c01369 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Langmuir, v.36, no.28, pp.8240 - 8252 | - |
dc.identifier.wosid | 000555006400021 | - |
dc.citation.endPage | 8252 | - |
dc.citation.number | 28 | - |
dc.citation.startPage | 8240 | - |
dc.citation.title | Langmuir | - |
dc.citation.volume | 36 | - |
dc.contributor.affiliatedAuthor | SON, CHANG YUN | - |
dc.identifier.scopusid | 2-s2.0-85088493826 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | LIQUID-CRYSTALLINE PHASES | - |
dc.subject.keywordPlus | N-ALKYL CHAINS | - |
dc.subject.keywordPlus | SUPRAMOLECULAR STRUCTURE | - |
dc.subject.keywordPlus | SALMONELLA-MINNESOTA | - |
dc.subject.keywordPlus | MOLECULAR-DYNAMICS | - |
dc.subject.keywordPlus | CUBIC PHASES | - |
dc.subject.keywordPlus | FORCE-FIELD | - |
dc.subject.keywordPlus | MICELLES | - |
dc.subject.keywordPlus | TRANSITIONS | - |
dc.subject.keywordPlus | DIAGRAM | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.