DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwon, Taewan | - |
dc.contributor.author | Kumari, Nitee | - |
dc.contributor.author | Kumar, Amit | - |
dc.contributor.author | Lim, Jongwon | - |
dc.contributor.author | Son, Chang Yun | - |
dc.contributor.author | Lee, In Su | - |
dc.date.accessioned | 2021-09-03T03:51:27Z | - |
dc.date.available | 2021-09-03T03:51:27Z | - |
dc.date.created | 2021-08-13 | - |
dc.date.issued | 2021-08 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/106793 | - |
dc.description.abstract | Nanostructures converting chemical energy to mechanical work by using benign metabolic fuels, have huge implications in biomedical science. Here, we introduce Au/Pt-based Janus nanostructures, resembling to "egg-in-nest" morphology (Au/Pt-ENs), showing enhanced motion as a result of dual enzyme-relay-like catalytic cascade in physiological biomedia, and in turn showing molecular-laden transport to living cells. We developed dynamic-casting approach using silica yolk-shell nanoreactors: first, to install a large Au-seed fixing the silica-yolk aside while providing the anisotropically confined concave hollow nanospace to grow curved Pt-dendritic networks. Owing to the intimately interfaced Au and Pt catalytic sites integrated in a unique anisotropic nest-like morphology, Au/Pt-ENs exhibited high diffusion rates and displacements as the result of glucose-converted oxygen concentration gradient. High diffusiophoresis in cell culture media increased the nanomotor-membrane interaction events, in turn facilitated the cell internalization. In addition, the porous network of Au/Pt-ENs facilitated the drug-molecule cargo loading and delivery to the living cells. | - |
dc.language | English | - |
dc.publisher | John Wiley & Sons Ltd. | - |
dc.relation.isPartOf | Angewandte Chemie - International Edition | - |
dc.title | Au/Pt‐Egg‐in‐Nest Nanomotor for Glucose‐Powered Catalytic Motion and Enhanced Molecular Transport to Living Cells | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/anie.202103827 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Angewandte Chemie - International Edition, v.60, no.32, pp.17579 - 17586 | - |
dc.identifier.wosid | 000666888200001 | - |
dc.citation.endPage | 17586 | - |
dc.citation.number | 32 | - |
dc.citation.startPage | 17579 | - |
dc.citation.title | Angewandte Chemie - International Edition | - |
dc.citation.volume | 60 | - |
dc.contributor.affiliatedAuthor | Son, Chang Yun | - |
dc.contributor.affiliatedAuthor | Lee, In Su | - |
dc.identifier.scopusid | 2-s2.0-85108850949 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | AU | - |
dc.subject.keywordPlus | NANOSTRUCTURES | - |
dc.subject.keywordPlus | OXIDATION | - |
dc.subject.keywordPlus | TRACKING | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | SHELL | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordAuthor | glucose fuel | - |
dc.subject.keywordAuthor | intracellular delivery carrier | - |
dc.subject.keywordAuthor | nanobowl | - |
dc.subject.keywordAuthor | nanocasting synthesis | - |
dc.subject.keywordAuthor | nanomotor | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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