DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nishi, K | - |
dc.contributor.author | Lee, HJ | - |
dc.contributor.author | Park, SY | - |
dc.contributor.author | Bae, SJ | - |
dc.contributor.author | Lee, SE | - |
dc.contributor.author | Adams, PD | - |
dc.contributor.author | Rhee, JH | - |
dc.contributor.author | Kim, JS | - |
dc.date.accessioned | 2022-01-10T06:40:06Z | - |
dc.date.available | 2022-01-10T06:40:06Z | - |
dc.date.created | 2021-07-05 | - |
dc.date.issued | 2010-03 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/109130 | - |
dc.description.abstract | HlyU is a transcription factor of the ArsR/SmtB family and activates the expression of the pathogenic Vibrio vulnificus RTX toxin. In contrast to the other metal-responding ArsR/SmtB proteins, HlyU does not sense metal ions. To provide its structural information, we elucidated the crystal structure of HlyU from V. vulnificus CMCP6 (HlyU_Vv). The monomeric HlyU_Vv architecture of five alpha-helices and two beta-strands, some of which constitute a typical DNA-binding winged helix-turn-helix (wHTH) motif, is very similar to that of other transcription regulators. Nonetheless, the homo-dimeric HlyU_Vv structure shows several different, three-dimensional features in the spatial position and the detailed dimeric interaction, which were not observed in the modeling study based on the same protein family and sequence similarity. Structured summary: MINT-7710072, MINT-7710086: HlyU_Vv ( uniprotkb: Q8DES3) and HlyU_Vv (uniprotkb: Q8DES3) bind (MI: 0407) by X-ray crystallography (MI: 0114) (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | Elsevier BV | - |
dc.relation.isPartOf | FEBS Letters | - |
dc.title | Crystal structure of the transcriptional activator HlyU from Vibrio vulnificus CMCP6 | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.febslet.2010.02.052 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | FEBS Letters, v.584, no.6, pp.1097 - 1102 | - |
dc.identifier.wosid | 000275738700005 | - |
dc.citation.endPage | 1102 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1097 | - |
dc.citation.title | FEBS Letters | - |
dc.citation.volume | 584 | - |
dc.contributor.affiliatedAuthor | Park, SY | - |
dc.identifier.scopusid | 2-s2.0-77950370125 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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