DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ding, Yuanmeng | - |
dc.contributor.author | Park, Byullee | - |
dc.contributor.author | Ye, Jiamin | - |
dc.contributor.author | Wang, Xiaojie | - |
dc.contributor.author | Liu, Gengqi | - |
dc.contributor.author | Yang, Xingyue | - |
dc.contributor.author | Jiang, Zhen | - |
dc.contributor.author | Han, Moongyu | - |
dc.contributor.author | Fan, Yong | - |
dc.contributor.author | Song, Jibin | - |
dc.contributor.author | Kim, Chulhong | - |
dc.contributor.author | Zhang, Yumiao | - |
dc.date.accessioned | 2022-02-28T04:40:13Z | - |
dc.date.available | 2022-02-28T04:40:13Z | - |
dc.date.created | 2022-02-28 | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/109568 | - |
dc.description.abstract | Photoacoustic imaging (PA) in the second near infrared (NIR-II) window presents key advantages for deep tissue imaging owing to reduced light scattering and low background signal from biological structures. Here, a thiadiazoloquinoxaline-based semiconducting polymer (SP) with strong absorption in the NIR-II region is reported. After encapsulation of SP in Pluronic F127 (F127) followed by removal of excess surfactant, a dual functional polymer system named surfactant-stripped semiconductor polymeric micelles (SSS-micelles) are generated with water solubility, storage stability, and high photothermal conversion efficiency, permitting tumor theranostics in a mouse model. SSS-micelles have a wideband absorption in the NIR-II window, allowing for the PA imaging at both 1064 and 1300 nm wavelengths. The PA signal of the SSS-micelles can be detected through 6.5 cm of chicken breast tissue in vitro. In mice or rats, SSS-micelles can be visualized in bladder and intestine overlaid 5 cm (signal to noise ratio, SNR approximate to 17 dB) and 5.8 cm (SNR over 10 dB) chicken breast tissue, respectively. This work demonstrates the SSS-micelles as a nanoplatform for deep tissue theranostics. | - |
dc.language | English | - |
dc.publisher | Wiley - V C H Verlag GmbbH & Co. | - |
dc.relation.isPartOf | Small | - |
dc.title | Surfactant‐Stripped Semiconducting Polymer Micelles for Tumor Theranostics and Deep Tissue Imaging in the NIR‐II Window | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/smll.202104132 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Small, v.18, no.6 | - |
dc.identifier.wosid | 000724121400001 | - |
dc.citation.number | 6 | - |
dc.citation.title | Small | - |
dc.citation.volume | 18 | - |
dc.contributor.affiliatedAuthor | Han, Moongyu | - |
dc.contributor.affiliatedAuthor | Kim, Chulhong | - |
dc.identifier.scopusid | 2-s2.0-85120360232 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | NEAR-INFRARED WINDOW | - |
dc.subject.keywordPlus | GASTROINTESTINAL-TRACT | - |
dc.subject.keywordPlus | PHOTOTHERMAL THERAPY | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | ABSORBENCY | - |
dc.subject.keywordPlus | AGENTS | - |
dc.subject.keywordAuthor | deep tissue imaging | - |
dc.subject.keywordAuthor | photoacoustic imaging | - |
dc.subject.keywordAuthor | second near infrared window | - |
dc.subject.keywordAuthor | semiconducting polymers | - |
dc.subject.keywordAuthor | surfactant-stripped micelles | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
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