DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Mincheol | - |
dc.contributor.author | Yoon, Taehee | - |
dc.contributor.author | Yang, Byeongseon | - |
dc.contributor.author | Cha, Hyung Joon | - |
dc.date.accessioned | 2022-06-22T00:20:31Z | - |
dc.date.available | 2022-06-22T00:20:31Z | - |
dc.date.created | 2022-04-28 | - |
dc.date.issued | 2022-03 | - |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/112949 | - |
dc.description.abstract | © 2022 American Chemical Society. All rights reserved.3,4-Dihydroxyphenylalanine (Dopa) is a versatile molecule that enables marine mussels to achieve successful underwater adhesion. However, due to its complicated redox chemistry and vulnerability to oxidation, controlling surface adhesion and cohesion has been a challenging issue to overcome. Foot protein type 6 (fp-6), a thiol-rich interfacial mussel adhesive protein, has been reported as a proteinaceous antioxidant for mussels that helps Dopa maintain surface adhesion ability. In this study, we focused on the role of fp-6 in oxidized Dopa. The effect on the tautomer equilibrium of oxidized Dopa was investigated using recombinant fp-6 (rfp-6) and Dopa-incorporated foot protein type 3 fast variant (drfp-3F), which were produced in bacterial cells. The redox chemistry of Dopa in drfp-3F and the role of rfp-6 were observed using a UV-vis spectrophotometer and a surface forces apparatus (SFA). We discovered that rfp-6 shifts the tautomer equilibrium to ΔDopa as a preferred tautomer for oxidized Dopa in drfp-3F and makes drfp-3F better on underwater surface adhesion. | - |
dc.language | English | - |
dc.publisher | American Chemical Society | - |
dc.relation.isPartOf | Langmuir | - |
dc.title | Thiol-Rich fp-6 Controls the Tautomer Equilibrium of Oxidized Dopa in Interfacial Mussel Foot Proteins | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acs.langmuir.1c03239 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Langmuir, v.38, no.11, pp.3446 - 3452 | - |
dc.identifier.wosid | 000778529600012 | - |
dc.citation.endPage | 3452 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3446 | - |
dc.citation.title | Langmuir | - |
dc.citation.volume | 38 | - |
dc.contributor.affiliatedAuthor | Shin, Mincheol | - |
dc.contributor.affiliatedAuthor | Yoon, Taehee | - |
dc.contributor.affiliatedAuthor | Yang, Byeongseon | - |
dc.contributor.affiliatedAuthor | Cha, Hyung Joon | - |
dc.identifier.scopusid | 2-s2.0-85126598463 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | ALPHA,BETA-DEHYDRO-3,4-DIHYDROXYPHENYLALANINE DERIVATIVES | - |
dc.subject.keywordPlus | SURFACE-ADHESION | - |
dc.subject.keywordPlus | WET ADHESION | - |
dc.subject.keywordPlus | CATECHOL | - |
dc.subject.keywordPlus | SYNERGY | - |
dc.subject.keywordPlus | REDOX | - |
dc.subject.keywordPlus | COHESION | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
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