Artificial water channels enable fast and selective water permeation through water-wire networks
SCIE
SCOPUS
- Title
- Artificial water channels enable fast and selective water permeation through water-wire networks
- Authors
- Song, Woochul; Joshi, Himanshu; Chowdhury, Ratul; Najem, Joseph S.; Shen, Yue-xiao; Lang, Chao; Henderson, Codey B.; Tu, Yu-Ming; Farell, Megan; Pitz, Megan E.; Maranas, Costas D.; Cremer, Paul S.; Hickey, Robert J.; Sarles, Stephen A.; Hou, Jun-li; Aksimentiev, Aleksei; Kumar, Manish
- Date Issued
- 2020-01
- Publisher
- Nature Publishing Group
- Abstract
- Artificial water channels are synthetic molecules that aim to mimic the structural and functional features of biological water channels (aquaporins). Here we report on a cluster-forming organic nanoarchitecture, peptide-appended hybrid[4]arene (PAH[4]), as a new class of artificial water channels. Fluorescence experiments and simulations demonstrated that PAH[4]s can form, through lateral diffusion, clusters in lipid membranes that provide synergistic membrane-spanning paths for a rapid and selective water permeation through water-wire networks. Quantitative transport studies revealed that PAH[4]s can transport >109 water molecules per second per molecule, which is comparable to aquaporin water channels. The performance of these channels exceeds the upper bound limit of current desalination membranes by a factor of ~104, as illustrated by the water/NaCl permeability–selectivity trade-off curve. PAH[4]’s unique properties of a high water/solute permselectivity via cooperative water-wire formation could usher in an alternative design paradigm for permeable membrane materials in separations, energy production and barrier applications. © 2019, The Author(s), under exclusive licence to Springer Nature Limited.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/116230
- DOI
- 10.1038/s41565-019-0586-8
- ISSN
- 1748-3387
- Article Type
- Article
- Citation
- Nature Nanotechnology, vol. 15, no. 1, page. 73 - 79, 2020-01
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