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Ratiometric fluorescence detection of cysteine and homocysteine with a BODIPY dye by mimicking the native chemical ligation
- Title
- Ratiometric fluorescence detection of cysteine and homocysteine with a BODIPY dye by mimicking the native chemical ligation
- Date Issued
- 2015-01
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- The selective detection of cysteine and homocysteine over glutathione and other amino acids was demonstrated with an 8-MeS-BODIPY probe by mimicking the native chemical ligation approach, which allowed the selective and ratiometric fluorescence sensing of cysteine over other biothiols at physiologically relevant concentrations and in different organs of a zebrafish.
- Keywords
- LARGE EMISSION SHIFT; HIGHLY SELECTIVE DETECTION; CHEMODOSIMETER; SENSOR; DISEASE; MECHANISM; GLUTATHIONE; THIOL PROBE; OXIDATIVE STRESS; LIVING CELLS
- ISSN
- 0003-2654
- Article Type
- Article
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