DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moonwoo La | - |
dc.contributor.author | Sang Min Park | - |
dc.contributor.author | Kim, DS | - |
dc.date.accessioned | 2015-07-07T19:04:46Z | - |
dc.date.available | 2015-07-07T19:04:46Z | - |
dc.date.created | 2015-01-19 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 1932-1058 | - |
dc.identifier.other | 2015-OAK-0000030703 | en_US |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/13074 | - |
dc.description.abstract | In this study, a multiple sample dispenser for precisely metered fixed volumes was successfully designed, fabricated, and fully characterized on a plastic centrifugal lab-on-a-disk (LOD) for parallel biochemical single-end-point assays. The dispenser, namely, a centrifugal multiplexing fixed-volume dispenser (C-MUFID) was designed with microfluidic structures based on the theoretical modeling about a centrifugal circumferential filling flow. The designed LODs were fabricated with a polystyrene substrate through micromachining and they were thermally bonded with a flat substrate. Furthermore, six parallel metering and dispensing assays were conducted at the same fixed-volume (1.27 mu l) with a relative variation of +/- 0.02 mu l. Moreover, the samples were metered and dispensed at different sub-volumes. To visualize the metering and dispensing performances, the C-MUFID was integrated with a serpentine micromixer during parallel centrifugal mixing tests. Parallel biochemical single-end-point assays were successfully conducted on the developed LOD using a standard serum with albumin, glucose, and total protein reagents. The developed LOD could be widely applied to various biochemical single-end-point assays which require different volume ratios of the sample and reagent by controlling the design of the C-MUFID. The proposed LOD is feasible for point-of-care diagnostics because of its mass-producible structures, reliable metering/dispensing performance, and parallel biochemical single-end-point assays, which can identify numerous biochemical. (c) 2015 AIP Publishing LLC. | - |
dc.description.statementofresponsibility | open | en_US |
dc.language | English | - |
dc.publisher | AMER INST PHYSICS | - |
dc.relation.isPartOf | BIOMICROFLUIDICS | - |
dc.rights | BY_NC_ND | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.0/kr | en_US |
dc.subject | FILLING FLOW | - |
dc.subject | MICROCHANNEL | - |
dc.subject | DEVICE | - |
dc.subject | FORCE | - |
dc.title | Centrifugal Multiplexing Fixed-Volume Dispenser on a Plastic Lab-on-a-Disk for Parallel Biochemical Single-End-Point Assays | - |
dc.type | Article | - |
dc.contributor.college | 기계공학과 | en_US |
dc.identifier.doi | 10.1063/1.4905940 | - |
dc.author.google | La, M | en_US |
dc.author.google | Park, SM | en_US |
dc.author.google | Kim, DS | en_US |
dc.relation.volume | 9 | en_US |
dc.relation.issue | 1 | en_US |
dc.relation.startpage | 14104 | en_US |
dc.contributor.id | 10170232 | en_US |
dc.relation.journal | BIOMICROFLUIDICS | en_US |
dc.relation.index | SCI급, SCOPUS 등재논문 | en_US |
dc.relation.sci | SCI | en_US |
dc.collections.name | Journal Papers | en_US |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOMICROFLUIDICS, v.9, no.1, pp.14104 | - |
dc.identifier.wosid | 000350546900004 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 14104 | - |
dc.citation.title | BIOMICROFLUIDICS | - |
dc.citation.volume | 9 | - |
dc.contributor.affiliatedAuthor | Sang Min Park | - |
dc.contributor.affiliatedAuthor | Kim, DS | - |
dc.identifier.scopusid | 2-s2.0-84923806215 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 2 | - |
dc.description.scptc | 2 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | FILLING FLOW | - |
dc.subject.keywordPlus | MICROCHANNEL | - |
dc.subject.keywordPlus | DEVICE | - |
dc.subject.keywordPlus | FORCE | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Physics, Fluids & Plasmas | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Physics | - |
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