Tracking X-ray microscopy for alveolar dynamics in live intact mice
SCIE
SCOPUS
- Title
- Tracking X-ray microscopy for alveolar dynamics in live intact mice
- Authors
- Chang, S; Kwon, N; Weon, BM; Kim, J; Rhee, CK; Choi, HS; Kohmura, Y; Yamamoto, M; Ishikawa, T; Je, JH
- Date Issued
- 2013-02-18
- Publisher
- Nature Publishing Group
- Abstract
- Here we report a tracking X-ray microscopy (TrXM) as a novel methodology by using upper right lung apices alveoli in live intact mice. By enabling tracking of individual alveolar movements during respiration, TrXM identifies alveolar dynamics: individual alveoli in the upper lung apices show a small size increment as 4.9 +/- 0.4% (mean +/- s.e.m.) during respiration while their shapes look almost invariant. TrXM analysis in alveolar dynamics would be significant for better understanding of alveolar-based diseases, for instance, ventilator induced lung injury (VILI) in acute respiratory distress syndrome (ARDS).
- Keywords
- ACUTE LUNG INJURY
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/13130
- DOI
- 10.1038/SREP01304
- ISSN
- 2045-2322
- Article Type
- Article
- Citation
- Scientific Reports, vol. 3, 2013-02-18
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