DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, GW | - |
dc.contributor.author | Chung, B | - |
dc.contributor.author | Jung, GY | - |
dc.contributor.author | Jung, GY | - |
dc.date.accessioned | 2016-03-31T07:42:01Z | - |
dc.date.available | 2016-03-31T07:42:01Z | - |
dc.date.created | 2015-02-09 | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 0173-0835 | - |
dc.identifier.other | 2014-OAK-0000031501 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/13917 | - |
dc.description.abstract | In this genomic era, the ability to assay multiple genomic hot spots that have strong clinical implications is greatly desired. Conventional PCR-based methods suffer from frequent false-positive detections, particularly when a multiplex analysis is desirable. As an alternative to the error-prone conventional methods, multiplex ligase-based genotyping methods combined with CE have a strong potential. In this review, both previously developed methods and emerging methods are described to reveal the specificity, sensitivity, and simplicity of the ligase-based methods. For each step (ligation, amplification, and separation), the principles of several alternative methods are discussed along with their applications to explore the future development of ligase-based diagnostic methods. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.relation.isPartOf | ELECTROPHORESIS | - |
dc.subject | CE | - |
dc.subject | Diagnostic methods | - |
dc.subject | Genetic polymorphisms | - |
dc.subject | Ligase-based genotyping | - |
dc.subject | Multiplex analysis | - |
dc.subject | DEPENDENT PROBE AMPLIFICATION | - |
dc.subject | ROLLING CIRCLE AMPLIFICATION | - |
dc.subject | SENSITIVE CAPILLARY-ELECTROPHORESIS | - |
dc.subject | SOLUTION CONJUGATE ELECTROPHORESIS | - |
dc.subject | MOLECULAR INVERSION PROBES | - |
dc.subject | COPY NUMBER VARIATION | - |
dc.subject | CHAIN-REACTION | - |
dc.subject | DNA-LIGASE | - |
dc.subject | MICROCHIP ELECTROPHORESIS | - |
dc.subject | MUTATION DETECTION | - |
dc.title | Multiplex ligase-based genotyping methods combined with CE | - |
dc.type | Article | - |
dc.contributor.college | 화학공학과 | - |
dc.identifier.doi | 10.1002/ELPS.201300361 | - |
dc.author.google | Shin, GW | - |
dc.author.google | Chung, B | - |
dc.author.google | Jung, GY | - |
dc.relation.volume | 35 | - |
dc.relation.issue | 7 | - |
dc.relation.startpage | 1004 | - |
dc.relation.lastpage | 1016 | - |
dc.contributor.id | 10130678 | - |
dc.relation.journal | ELECTROPHORESIS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ELECTROPHORESIS, v.35, no.7, pp.1004 - 1016 | - |
dc.identifier.wosid | 000333644600012 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 1016 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1004 | - |
dc.citation.title | ELECTROPHORESIS | - |
dc.citation.volume | 35 | - |
dc.contributor.affiliatedAuthor | Jung, GY | - |
dc.identifier.scopusid | 2-s2.0-84897382585 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 4 | - |
dc.description.scptc | 4 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Review | - |
dc.subject.keywordPlus | DEPENDENT PROBE AMPLIFICATION | - |
dc.subject.keywordPlus | ROLLING CIRCLE AMPLIFICATION | - |
dc.subject.keywordPlus | SENSITIVE CAPILLARY-ELECTROPHORESIS | - |
dc.subject.keywordPlus | SOLUTION CONJUGATE ELECTROPHORESIS | - |
dc.subject.keywordPlus | MOLECULAR INVERSION PROBES | - |
dc.subject.keywordPlus | COPY NUMBER VARIATION | - |
dc.subject.keywordPlus | CHAIN-REACTION | - |
dc.subject.keywordPlus | DNA-LIGASE | - |
dc.subject.keywordPlus | MICROCHIP ELECTROPHORESIS | - |
dc.subject.keywordPlus | MUTATION DETECTION | - |
dc.subject.keywordAuthor | CE | - |
dc.subject.keywordAuthor | Diagnostic methods | - |
dc.subject.keywordAuthor | Genetic polymorphisms | - |
dc.subject.keywordAuthor | Ligase-based genotyping | - |
dc.subject.keywordAuthor | Multiplex analysis | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
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