Intense acoustic bursts as a signal-enhancement mechanism in ultrasound-modulated optical tomography
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SCOPUS
- Title
- Intense acoustic bursts as a signal-enhancement mechanism in ultrasound-modulated optical tomography
- Authors
- Kim, C; Zemp, RJ; Wang, LHV
- Date Issued
- 2006-08-15
- Publisher
- OSA
- Abstract
- Biophotonic imaging with ultrasound-modulated optical tomography (UOT) promises ultrasonically resolved imaging in biological tissues. A key challenge in this imaging technique is a low signal-to-noise ratio (SNR). We show significant UOT signal enhancement by using intense time-gated acoustic bursts. A CCD camera captured the speckle pattern from a laser-illuminated tissue phantom. Differences in speckle contrast were observed when ultrasonic bursts were applied, compared with when no ultrasound was applied. When CCD triggering was synchronized with burst initiation, acoustic-radiation-force-induced displacements were detected. To avoid mechanical contrast in UOT images, the CCD camera acquisition was delayed several milliseconds until transient effects of acoustic radiation force attenuated to a satisfactory level. The SNR of our system was sufficiently high to provide an image pixel per acoustic burst-without signal averaging. Because of the substantially improved SNR, the use of intense acoustic bursts is a promising signal enhancement strategy for UOT. (c) 2006 Optical Society of America.
- Keywords
- BIOLOGICAL TISSUE; RADIATION FORCE; LIGHT; MEDIA; PHOTONS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/15346
- DOI
- 10.1364/OL.31.002423
- ISSN
- 0146-9592
- Article Type
- Article
- Citation
- Optics Letters, vol. 31, no. 16, page. 2423 - 2425, 2006-08-15
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- There are no files associated with this item.
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