DC Field | Value | Language |
---|---|---|
dc.contributor.author | Alej | - |
dc.contributor.author | ro, S | - |
dc.contributor.author | Lee, Y | - |
dc.contributor.author | Tohge, T | - |
dc.contributor.author | Sudre, D | - |
dc.contributor.author | Osorio, S | - |
dc.contributor.author | Park, J | - |
dc.contributor.author | Bovet, L | - |
dc.contributor.author | Lee, Y | - |
dc.contributor.author | Geldner, N | - |
dc.contributor.author | Fernie, AR | - |
dc.contributor.author | Martinoia, E | - |
dc.date.accessioned | 2016-03-31T08:43:19Z | - |
dc.date.available | 2016-03-31T08:43:19Z | - |
dc.date.created | 2013-03-07 | - |
dc.date.issued | 2012-07-10 | - |
dc.identifier.issn | 0960-9822 | - |
dc.identifier.other | 2012-OAK-0000026861 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/15902 | - |
dc.description.abstract | Lignin is the defining constituent of wood and the second most abundant natural polymer on earth. Lignin is produced by the oxidative coupling of three monolignols: p-coumaryl alcohol, coniferyl alcohol, and sinapyl alcohol [1]. Mono lignols are synthesized via the phenylpropanoid pathway and eventually polymerized in the cell wall by peroxidases and laccases. However, the mechanism whereby monolignols are transported from the cytosol to the cell wall has remained elusive. Here we report the discovery that AtABCG29, an ATP-binding cassette transporter, acts as a p-coumaryl alcohol transporter. Expression of AtABCG29 promoter-driven reporter genes and a Citrine-AtABCG29 fusion construct revealed that AtABCG29 is targeted to the plasma membrane of the root endodermis and vascular tissue. Moreover, yeasts expressing AtABCG29 exhibited an increased tolerance to p-coumaryl alcohol by excreting this monolignol. Vesicles isolated from yeasts expressing AtABCG29 exhibited a p-coumaryl alcohol transport activity. Loss-of-function Arabidopsis mutants contained less lignin subunits and were more sensitive to p-coumaryl alcohol. Changes in secondary metabolite profiles in abcg29 underline the importance of regulating p-coumaryl alcohol levels in the cytosol. This is the first identification of a monolignol transporter, closing a crucial gap in our understanding of lignin biosynthesis, which could open new directions for lignin engineering. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | CURRENT BIOLOGY | - |
dc.relation.isPartOf | CURRENT BIOLOGY | - |
dc.subject | ARABIDOPSIS-THALIANA | - |
dc.subject | PLANT DEVELOPMENT | - |
dc.subject | ABC TRANSPORTERS | - |
dc.subject | PRECURSORS | - |
dc.subject | DIFFERENTIATION | - |
dc.subject | ACCUMULATION | - |
dc.subject | GENETICS | - |
dc.subject | STRESS | - |
dc.subject | FAMILY | - |
dc.subject | GROWTH | - |
dc.title | AtABCG29 is a monolignol transporter involved in lignin biosynthesis | - |
dc.type | Article | - |
dc.contributor.college | 융합생명공학부 | - |
dc.identifier.doi | 10.1016/J.CUB.2012.04.064 | - |
dc.author.google | Alejandro, S | - |
dc.author.google | Lee, Y | - |
dc.author.google | Tohge, T | - |
dc.author.google | Sudre, D | - |
dc.author.google | Osorio, S | - |
dc.author.google | Park, J | - |
dc.author.google | Bovet, L | - |
dc.author.google | Geldner, N | - |
dc.author.google | Fernie, AR | - |
dc.author.google | Martinoia, E | - |
dc.relation.volume | 22 | - |
dc.relation.issue | 13 | - |
dc.relation.startpage | 1207 | - |
dc.relation.lastpage | 1212 | - |
dc.contributor.id | 10175128 | - |
dc.relation.journal | CURRENT BIOLOGY | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CURRENT BIOLOGY, v.22, no.13, pp.1207 - 1212 | - |
dc.identifier.wosid | 000306379600025 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 1212 | - |
dc.citation.number | 13 | - |
dc.citation.startPage | 1207 | - |
dc.citation.title | CURRENT BIOLOGY | - |
dc.citation.volume | 22 | - |
dc.contributor.affiliatedAuthor | ro, S | - |
dc.identifier.scopusid | 2-s2.0-84863727506 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 106 | - |
dc.description.scptc | 98 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | ARABIDOPSIS-THALIANA | - |
dc.subject.keywordPlus | PLANT DEVELOPMENT | - |
dc.subject.keywordPlus | ABC TRANSPORTERS | - |
dc.subject.keywordPlus | PRECURSORS | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | ACCUMULATION | - |
dc.subject.keywordPlus | GENETICS | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | FAMILY | - |
dc.subject.keywordPlus | GROWTH | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalResearchArea | Cell Biology | - |
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