Label-Free Polypeptide-Based Enzyme Detection Using a Graphene-Nanoparticle Hybrid Sensor
SCIE
SCOPUS
- Title
- Label-Free Polypeptide-Based Enzyme Detection Using a Graphene-Nanoparticle Hybrid Sensor
- Authors
- Sung Myung; Perry T. Yin; Cheoljin Kim; Jaesung Park; Aniruddh Solanki; Reyes, PI; Yicheng Lu; Kim, KS; Ki-Bum Lee
- Date Issued
- 2012-11-27
- Publisher
- WILEY-BLACKWELL
- Abstract
- A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface. [GRAPHICS] .
- Keywords
- FIELD-EFFECT-TRANSISTOR; SUSPENDED GRAPHENE; PROTEIN; OXIDE; DEVICES; BIOSENSORS; TRANSPORT; MOBILITY; COMPLEX; FILMS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/16202
- DOI
- 10.1002/ADMA.201202961
- ISSN
- 0935-9648
- Article Type
- Article
- Citation
- ADVANCED MATERIALS, vol. 24, no. 45, page. 6081 - 6087, 2012-11-27
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- There are no files associated with this item.
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