Imaging efficiency of an X-ray contrast agent-incorporated polymeric microparticle
SCIE
SCOPUS
- Title
- Imaging efficiency of an X-ray contrast agent-incorporated polymeric microparticle
- Authors
- Sung Sook Ahn; Sung Yong Jung; Lee, JP; Lee, SJ
- Date Issued
- 2011-11
- Publisher
- Wiley & Sons
- Abstract
- Biocompatible polymeric encapsulants have been widely used as a delivery vehicle for a variety of drugs and imaging agents. In this study, X-ray contrast agent (iopamidol) is encapsulated into a polymeric microparticle (polyvinyl alcohol) as a particulate flow tracer in synchrotron X-ray imaging system. The physical properties of the designed microparticles are investigated and correlated with enhancement in the imaging efficiency by experimental observation and theoretical interpretation. The X-ray absorption ability of the designed microparticle is assessed by BeerLambertBouguer law. Particle size, either in dried state or in solvent, primarily dominates the X-ray absorption ability under the given condition, thus affecting imaging efficiency of the designed X-ray contrast flow tracers. Copyright (C) 2011 John Wiley & Sons, Ltd.
- Keywords
- X-ray contrast agents; microparticles; Beer-Lambert-Bouguer law; X-ray imaging; imaging efficiency; hydrodynamic size (DH); IODINATED NANOPARTICLES; FLOW; VELOCIMETRY
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/16970
- DOI
- 10.1002/CMMI.440
- ISSN
- 1555-4309
- Article Type
- Article
- Citation
- CONTRAST MEDIA & MOLECULAR IMAGING, vol. 6, no. 6, page. 437 - 448, 2011-11
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