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Cardiac outflow and wall motion in hypothermic chick embryos SCIE SCOPUS

Title
Cardiac outflow and wall motion in hypothermic chick embryos
Authors
Lee, SJEun Seop YeomHo Jin HaKwon Ho Nam
Date Issued
2011-11
Publisher
ELSEVIER
Abstract
Cardiac outflow in the early developmental stage of a chick embryo is known to be highly variable depending on environmental temperature. To investigate the effects of environmental hypothermia on the blood flow in the outflow tract (OFT) of chick embryonic hearts, microscopic flow images were consecutively captured from chick embryos at HH stage 17 (2.5 days of incubation) at room temperature. Instantaneous velocity field information of blood flow in OFT was obtained using a micro-particle image velocimetry technique. The cyclic variations of the OFT vessel diameter and wall thickness were simultaneously measured. The experimental results show that environmental hypothermia causes bradycardia with a decrease in peak velocity during systole and the occurrence of backflow during diastole in the OFT. These abnormal phenomena seem to be attributed to the suppression of myocardial wall motion under hypothermic conditions. (C) 2011 Elsevier Inc. All rights reserved.
Keywords
OPTICAL COHERENCE TOMOGRAPHY; VITELLINE-VEIN LIGATION; BLOOD-FLOW; STAGE 18; ENVIRONMENTAL HYPOTHERMIA; EPIGENETIC FACTOR; HEART TUBE; IN-VITRO; MICROCIRCULATION; HEMODYNAMICS
URI
https://oasis.postech.ac.kr/handle/2014.oak/16971
DOI
10.1016/J.MVR.2011.09.005
ISSN
0026-2862
Article Type
Article
Citation
MICROVASCULAR RESEARCH, vol. 82, no. 3, page. 296 - 303, 2011-11
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이상준LEE, SANG JOON
Dept of Mechanical Enginrg
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