Open Access System for Information Sharing

Login Library

 

Article
Cited 62 time in webofscience Cited 71 time in scopus
Metadata Downloads

Gold nanoparticle-incorporated human red blood cells (RBCs) for X-ray dynamic imaging SCIE SCOPUS

Title
Gold nanoparticle-incorporated human red blood cells (RBCs) for X-ray dynamic imaging
Authors
Ahn, SJung, SYSeo, ELee, SJ
Date Issued
2011-10
Publisher
ELSEVIER SCI LTD
Abstract
Time-resolved dynamic imaging of bio-fluids can provide valuable information for clinical diagnosis and treatment of circulatory disorders. Quantitative information on non-transparent blood flows can be directly obtained by particle-tracing dynamic X-ray imaging, which needs better spatial resolution and enhanced image contrast compared to static imaging. For that use, tracer particles tagging along the flow streams are critically required. In this study, taking the advantage of high X-ray absorption, gold nanoparticles (AuNPs) are incorporated into human red blood cells (RBC) to produce contrast-enhanced tracers designed for dynamic X-ray imaging of blood flows. RBCs are advantageous tracers for blood flow measurements since they are natural and primary components of blood. The loading efficiency of AuNPs into RBCs is investigated in terms of the surface properties of the AuNPs. The AuNP-incorporated RBC provides a potential in the dynamic X-ray imaging of blood flows which can be used for clinical applications. (C) 2011 Elsevier Ltd. All rights reserved.
Keywords
Gold nanoparticles; Red blood cells; Flow tracer; Dynamic X-ray imaging; DRUG-DELIVERY; MECHANISM; SIZE; PARTICLES; FLOW; ERYTHROCYTES; CHEMISTRY; MEMBRANES; PEPTIDES
URI
https://oasis.postech.ac.kr/handle/2014.oak/17064
DOI
10.1016/J.BIOMATERIALS.2011.05.023
ISSN
0142-9612
Article Type
Article
Citation
BIOMATERIALS, vol. 32, no. 29, page. 7191 - 7199, 2011-10
Files in This Item:
There are no files associated with this item.

qr_code

  • mendeley

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher

이상준LEE, SANG JOON
Dept of Mechanical Enginrg
Read more

Views & Downloads

Browse