DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, JH | - |
dc.contributor.author | Lee, JW | - |
dc.contributor.author | Jung, JH | - |
dc.contributor.author | Cho, DW | - |
dc.contributor.author | Lim, G | - |
dc.date.accessioned | 2016-03-31T09:36:02Z | - |
dc.date.available | 2016-03-31T09:36:02Z | - |
dc.date.created | 2011-06-16 | - |
dc.date.issued | 2011-08 | - |
dc.identifier.issn | 0022-2461 | - |
dc.identifier.other | 2011-OAK-0000023712 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/17382 | - |
dc.description.abstract | Synthetic polymers were used to fabricate a three-dimensional (3D) porous scaffold of poly(propylene fumarate)/diethyl fumarate (PPF/DEF). PPF-based materials are good candidates for bone regeneration, because of their non-toxic, biodegradable byproducts, and excellent mechanical properties. However, they exhibit hydrophobic surface properties that have negative effects on cell adhesion. To change the surface properties of a PPF/DEF scaffold, the authors used three peptide modifications (RGD, cyclo RGD, and RGD-KRSR mixture) to the scaffold and tested the effects on MC3T3-E1 pre-osteoblast adhesion, proliferation, and differentiation. The results indicated that peptide modification (particularly the RGD-KRDR mixture) altered the hydrophobic surface properties of the PPF/DEF scaffold, and promoted cell adhesion. Thus, it was suggest that peptide modification is a useful method for changing the properties of the PPF/DEF scaffold surface and may be applicable in bone tissue engineering. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | JOURNAL OF MATERIALS SCIENCE | - |
dc.subject | OSTEOBLAST-ADHESIVE PEPTIDES | - |
dc.subject | MICRO-STEREOLITHOGRAPHY | - |
dc.subject | RGD PEPTIDE | - |
dc.subject | BIOMATERIALS | - |
dc.subject | SURFACES | - |
dc.title | Evaluation of cell proliferation and differentiation on a poly(propylene fumarate) 3D scaffold treated with functional peptides | - |
dc.type | Article | - |
dc.contributor.college | 융합생명공학부 | - |
dc.identifier.doi | 10.1007/S10853-011-5467-Y | - |
dc.author.google | Shin, JH | - |
dc.author.google | Lee, JW | - |
dc.author.google | Jung, JH | - |
dc.author.google | Cho, DW | - |
dc.author.google | Lim, G | - |
dc.relation.volume | 46 | - |
dc.relation.issue | 15 | - |
dc.relation.startpage | 5282 | - |
dc.relation.lastpage | 5287 | - |
dc.contributor.id | 10102903 | - |
dc.relation.journal | JOURNAL OF MATERIALS SCIENCE | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF MATERIALS SCIENCE, v.46, no.15, pp.5282 - 5287 | - |
dc.identifier.wosid | 000290453900035 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 5287 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 5282 | - |
dc.citation.title | JOURNAL OF MATERIALS SCIENCE | - |
dc.citation.volume | 46 | - |
dc.contributor.affiliatedAuthor | Cho, DW | - |
dc.contributor.affiliatedAuthor | Lim, G | - |
dc.identifier.scopusid | 2-s2.0-79956085929 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 17 | - |
dc.description.scptc | 16 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | OSTEOBLAST-ADHESIVE PEPTIDES | - |
dc.subject.keywordPlus | MICRO-STEREOLITHOGRAPHY | - |
dc.subject.keywordPlus | RGD PEPTIDE | - |
dc.subject.keywordPlus | BIOMATERIALS | - |
dc.subject.keywordPlus | SURFACES | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
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