Stereoselective synthesis of beta-amino alcohols: diastereoselective reduction of chiral alpha'-amino enones derived from amino acids
SCIE
SCOPUS
- Title
- Stereoselective synthesis of beta-amino alcohols: diastereoselective reduction of chiral alpha'-amino enones derived from amino acids
- Authors
- Chung, SK; Kang, DN
- Date Issued
- 1997-09-25
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- alpha-Amino acids are doubly benzylated at nitrogen to give N,N-dibenzyl amino adds, which can readily be converted to alpha'-amino enones 3. The alpha'-amino enones are very resistant to racemization, and undergo highly diastereoselective reduction to afford chiral amino alcohols upon treatment with L-Selectride under non-chelation control. (C) 1997 Elsevier Science Ltd.
- Keywords
- ORGANIC-SYNTHESIS; 2-AMINO ALCOHOLS; BUILDING-BLOCKS; ALDEHYDES; ADDITIONS; ACETALS; ESTERS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/21211
- DOI
- 10.1016/S0957-4166(97)00374-1
- ISSN
- 0957-4166
- Article Type
- Article
- Citation
- TETRAHEDRON-ASYMMETRY, vol. 8, no. 18, page. 3027 - 3030, 1997-09-25
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- There are no files associated with this item.
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