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Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A SCIE SCOPUS
- Title
- Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A
- Date Issued
- 2008-08-15
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure-activity relationship of Incentrom A for the anti-yeast activity were established. (C) 2008 Elsevier Ltd. All rights reserved.
- Keywords
- inhibition; chromosome segregation; yeast; structure-activity relationship; pharmacophore; incentrom A; CENTROMERE
- ISSN
- 0960-894X
- Article Type
- Article
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18, no. 16, page. 4670 - 4674, 2008-08-15
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Related Researcher
- 신승구SHIN, SEUNG KOO
- Dept of Chemistry