DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, G | - |
dc.contributor.author | Ree, M | - |
dc.contributor.author | Kim, H | - |
dc.contributor.author | Kim, IJ | - |
dc.contributor.author | Kim, JR | - |
dc.contributor.author | Lee, JI | - |
dc.date.accessioned | 2016-04-01T01:14:08Z | - |
dc.date.available | 2016-04-01T01:14:08Z | - |
dc.date.created | 2009-03-09 | - |
dc.date.issued | 2008-07 | - |
dc.identifier.issn | 1598-5032 | - |
dc.identifier.other | 2008-OAK-0000008018 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/22591 | - |
dc.description.abstract | In this study we investigated bacterial and cell adhesion to poly(propylene carbonate) (PPC) films, that had been synthesized by the copolymerization of carbon dioxide (a global warming chemical) with propylene oxide. We also assessed the biocompatibility and biodegradability of the films in vivo, and their oxidative degradation in vitro. The bacteria adhered to the smooth, hydrophobic PPC surface after 4 h incubation. Pseudomonas aeruginosa and Enterococcus faecalis had the highest levels of adhesion, Escherichia coli and Staphylococcus aureus had the lowest levels, and Staphylococcus epidermidis was intermediate. In contrast, there was no adhesion of human cells (cell line HEp-2) to the PPC films, due to the hydrophobicity and dimensional instability of the surface. On the other hand, the PPC films exhibited good biocompatibility in the mouse subcutaneous environment. Moreover, contrary to expectation the PPC films degraded in the mouse subcutaneous environment. This is the first experimental confirmation that PPC can undergo surface erosion biodegradation in vivo. The observed biodegradability of PPC may have resulted from enzymatic hydrolysis and oxidative degradation processes. In contrast, the PPC films showed resistance to oxidative degradation in vitro. Overall, PPC revealed high affinity to bioorganisms and also good biodegradability. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | POLYMER SOC KOREA | - |
dc.relation.isPartOf | MACROMOLECULAR RESEARCH | - |
dc.subject | poly(propylene carbonate) | - |
dc.subject | bacterial adhesion | - |
dc.subject | cell adhesion | - |
dc.subject | biocompatibility biodegradability | - |
dc.subject | ZINC GLUTARATE | - |
dc.subject | ALTERNATING COPOLYMERIZATION | - |
dc.subject | BACTERIAL ADHESION | - |
dc.subject | EPSILON-CAPROLACTONE | - |
dc.subject | SURFACE-PROPERTIES | - |
dc.subject | CELL-SURFACE | - |
dc.subject | IN-VIVO | - |
dc.subject | CATALYSTS | - |
dc.subject | CO2 | - |
dc.subject | DERIVATIVES | - |
dc.title | Biological affinity and biodegradability of poly(propylene carbonate) prepared from copolymerization of carbon dioxide with propylene oxide | - |
dc.type | Article | - |
dc.contributor.college | BK분자과학사업단 | - |
dc.identifier.doi | 10.1007/BF03218547 | - |
dc.author.google | Kim, G | - |
dc.author.google | Ree, M | - |
dc.author.google | Kim, H | - |
dc.author.google | Kim, IJ | - |
dc.author.google | Kim, JR | - |
dc.author.google | Lee, JI | - |
dc.relation.volume | 16 | - |
dc.relation.issue | 5 | - |
dc.relation.startpage | 473 | - |
dc.relation.lastpage | 480 | - |
dc.contributor.id | 10115761 | - |
dc.relation.journal | MACROMOLECULAR RESEARCH | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR RESEARCH, v.16, no.5, pp.473 - 480 | - |
dc.identifier.wosid | 000258264000014 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 480 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 473 | - |
dc.citation.title | MACROMOLECULAR RESEARCH | - |
dc.citation.volume | 16 | - |
dc.contributor.affiliatedAuthor | Ree, M | - |
dc.identifier.scopusid | 2-s2.0-49049107335 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 30 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | ZINC GLUTARATE | - |
dc.subject.keywordPlus | ALTERNATING COPOLYMERIZATION | - |
dc.subject.keywordPlus | BACTERIAL ADHESION | - |
dc.subject.keywordPlus | CELL-SURFACE | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | CO2 | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | CATALYSTS | - |
dc.subject.keywordPlus | POLYMER | - |
dc.subject.keywordAuthor | poly(propylene carbonate) | - |
dc.subject.keywordAuthor | bacterial adhesion | - |
dc.subject.keywordAuthor | cell adhesion | - |
dc.subject.keywordAuthor | biocompatibility biodegradability | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Polymer Science | - |
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