Fabrication of a SFF-based three-dimensional scaffold using a precision deposition system in tissue engineering
SCIE
SCOPUS
- Title
- Fabrication of a SFF-based three-dimensional scaffold using a precision deposition system in tissue engineering
- Authors
- Kim, JY; Park, EK; Kim, SY; Shin, JW; Cho, DW
- Date Issued
- 2008-05
- Publisher
- IOP PUBLISHING LTD
- Abstract
- Recent developments in tissue-engineering techniques allow physicians to treat a range of previously untreatable conditions. In the development of such techniques, scaffolds with a controllable pore size and porosity have been manufactured using solid free-form fabrication methods to investigate cell interaction effects such as cell proliferation and differentiation. In this study, we describe the fabrication of scaffolds from two types of biodegradable materials using a precision deposition system that we developed. The precision deposition system uses technology that enables the manufacture of three-dimensional (3D) microstructures. The fabrication of 3D tissue-engineering scaffolds using the precision deposition system required the combination of several technologies, including motion control, thermal control, pneumatic control and CAD/CAM software. Through the fabrication and cell interaction analysis of two kinds of scaffolds using polycaprolactone and poly-lactic-co-glycolic acid, feasibility of application to the tissue engineering of the developed SFF-based precision deposition system is demonstrated.
- Keywords
- MECHANICAL-PROPERTIES; BONE; BIOMATERIALS; COMPOSITES; DESIGN
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/22781
- DOI
- 10.1088/0960-1317/18/5/055027
- ISSN
- 0960-1317
- Article Type
- Article
- Citation
- JOURNAL OF MICROMECHANICS AND MICROENGINEERING, vol. 18, no. 5, 2008-05
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