DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dhonukshe, P | - |
dc.contributor.author | Aniento, F | - |
dc.contributor.author | Hwang, I | - |
dc.contributor.author | Robinson, DG | - |
dc.contributor.author | Mravec, J | - |
dc.contributor.author | Stierhof, YD | - |
dc.contributor.author | Friml, J | - |
dc.date.accessioned | 2016-04-01T01:41:43Z | - |
dc.date.available | 2016-04-01T01:41:43Z | - |
dc.date.created | 2009-08-12 | - |
dc.date.issued | 2007-03-20 | - |
dc.identifier.issn | 0960-9822 | - |
dc.identifier.other | 2007-OAK-0000006692 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/23499 | - |
dc.description.abstract | Endocytosis is an essential process by which eukaryotic cells internalize exogenous material or regulate signaling At the cell,surface [1]. Different endocytic pathways are well established in yeast and animals; prominent among them is clathrin-dependent endocytosis [2, 3]. In plants, endocytosis is poorly defined, and no molecular mechanism for cargo internalization has been demonstrated so far [4, 5], although the internalization of receptor-ligand complexes at the plant plasma membrane has recently been shown [6]. Here we demonstrate by means of a green-to-red photo-convertible fluorescent reporter, EosFP [7], the constitutive endocytosis of PIN auxin efflux carriers [8] and their recycling to the plasma membrane. Using a plant clathrin-specific antibody, we show the presence of clathrin at different stages of coated-vesicle formation at the plasma membrane in Arabidopsis. Genetic interference with clathrin function inhibits PIN internalization and endocytosis in general. Furthermore, pharmacological interference with cargo recruitment into the clathrin pathway blocks internalization of PINs and other plasma-membrane proteins. Our data demonstrate that clathrin-dependent endocytosis is operational in plants and constitutes the predominant pathway for the internalization of numerous plasma-membrane-resid nt proteins including PIN auxin efflux carriers. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | CELL PRESS | - |
dc.relation.isPartOf | CURRENT BIOLOGY | - |
dc.subject | TRANSFERRIN RECEPTOR | - |
dc.subject | FLUORESCENT MARKER | - |
dc.subject | TYRPHOSTIN A23 | - |
dc.subject | PLANT-CELLS | - |
dc.subject | BREFELDIN-A | - |
dc.subject | TRAFFICKING | - |
dc.subject | TRANSPORT | - |
dc.subject | GRADIENTS | - |
dc.subject | PROTEINS | - |
dc.subject | COMPLEX | - |
dc.title | Clathrin-mediated constitutive endocytosis of PIN auxin efflux carriers in Arabidopsis | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1016/J.CUB.2007.01.052 | - |
dc.author.google | Dhonukshe, P | - |
dc.author.google | Aniento, F | - |
dc.author.google | Hwang, I | - |
dc.author.google | Robinson, DG | - |
dc.author.google | Mravec, J | - |
dc.author.google | Stierhof, YD | - |
dc.author.google | Friml, J | - |
dc.relation.volume | 17 | - |
dc.relation.issue | 6 | - |
dc.relation.startpage | 520 | - |
dc.relation.lastpage | 527 | - |
dc.contributor.id | 10078446 | - |
dc.relation.journal | CURRENT BIOLOGY | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CURRENT BIOLOGY, v.17, no.6, pp.520 - 527 | - |
dc.identifier.wosid | 000245225500024 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 527 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 520 | - |
dc.citation.title | CURRENT BIOLOGY | - |
dc.citation.volume | 17 | - |
dc.contributor.affiliatedAuthor | Hwang, I | - |
dc.identifier.scopusid | 2-s2.0-33947152773 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 386 | - |
dc.description.scptc | 383 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | TRANSFERRIN RECEPTOR | - |
dc.subject.keywordPlus | FLUORESCENT MARKER | - |
dc.subject.keywordPlus | TYRPHOSTIN A23 | - |
dc.subject.keywordPlus | PLANT-CELLS | - |
dc.subject.keywordPlus | TRAFFICKING | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | GRADIENTS | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalResearchArea | Cell Biology | - |
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