The feasibility of fluorescent nano-particle for biological flow analysis in a microchannel

Abstract

The biological flow characteristics inside a microchannel were investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study were to understand the blood flow in micro-domain blood vessels and to identify the feasibility of nano-scale fluorescent particles for velocity measurement. The flow field was analyzed with a spatial resolution of 1Kx1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields were captured and ensemble-averaged. As a result, for the case of blood flow, there were substantial velocity variations in the central region of micro-channel due to the presence of blood cells in the blood flow.