DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, JH | - |
dc.contributor.author | Kim, CS | - |
dc.contributor.author | Hwang, BH | - |
dc.contributor.author | Cha, HJ | - |
dc.date.accessioned | 2016-04-01T02:33:35Z | - |
dc.date.available | 2016-04-01T02:33:35Z | - |
dc.date.created | 2010-12-06 | - |
dc.date.issued | 2010-05-28 | - |
dc.identifier.issn | 0957-4484 | - |
dc.identifier.other | 2010-OAK-0000022336 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/25354 | - |
dc.description.abstract | A carbohydrate chip based on glass or other transparent surfaces has been suggested as a potential tool for high-throughput analysis of carbohydrate-protein interactions. Here we proposed a facile, efficient, and cost-effective method whereby diverse carbohydrate types are modified in a single step and directly immobilized onto a glass surface, with retention of functional orientation. We modified various types of carbohydrates by reductive amination, in which reducing sugar groups were coupled with 4-(2-aminoethyl)aniline, which has di-amine groups at both ends. The modified carbohydrates were covalently attached to an amino-reactive NHS-activated glass surface by formation of stable amide bonds. This proposed method was applied for efficient construction of a carbohydrate microarray to analyze carbohydrate-protein interactions. The carbohydrate chip prepared using our method can be successfully used in diverse biomimetic studies of carbohydrates, including carbohydrate-biomolecule interactions, and carbohydrate sensor chip or microarray development for diagnosis and screening. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | IOP PUBLISHING LTD | - |
dc.relation.isPartOf | NANOTECHNOLOGY | - |
dc.subject | SELF-ASSEMBLED MONOLAYERS | - |
dc.subject | CHOLERA-TOXIN | - |
dc.subject | SUGAR CHAINS | - |
dc.subject | OLIGOSACCHARIDE MICROARRAYS | - |
dc.subject | BINDING | - |
dc.subject | SURFACE | - |
dc.subject | IMMOBILIZATION | - |
dc.subject | GLYCOSYLATION | - |
dc.subject | SPECIFICITY | - |
dc.subject | RECEPTOR | - |
dc.title | A functional carbohydrate chip platform for analysis of carbohydrate-protein interaction | - |
dc.type | Article | - |
dc.contributor.college | 화학공학과 | - |
dc.identifier.doi | 10.1088/0957-4484/21/21/215101 | - |
dc.author.google | Seo, JH | - |
dc.author.google | Kim, CS | - |
dc.author.google | Hwang, BH | - |
dc.author.google | Cha, HJ | - |
dc.relation.volume | 21 | - |
dc.relation.issue | 21 | - |
dc.contributor.id | 10057405 | - |
dc.relation.journal | NANOTECHNOLOGY | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | NANOTECHNOLOGY, v.21, no.21 | - |
dc.identifier.wosid | 000277215200001 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.number | 21 | - |
dc.citation.title | NANOTECHNOLOGY | - |
dc.citation.volume | 21 | - |
dc.contributor.affiliatedAuthor | Cha, HJ | - |
dc.identifier.scopusid | 2-s2.0-77951801349 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 13 | - |
dc.description.scptc | 15 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SUGAR CHAINS | - |
dc.subject.keywordPlus | OLIGOSACCHARIDE MICROARRAYS | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | SURFACE | - |
dc.subject.keywordPlus | IMMOBILIZATION | - |
dc.subject.keywordPlus | GLYCOSYLATION | - |
dc.subject.keywordPlus | SPECIFICITY | - |
dc.subject.keywordPlus | PYRIDYLAMINATION | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | AGGLUTININ | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
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