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Gold Nanoparticle Flow Sensors Designed for Dynamic X-ray Imaging in Biofluids SCIE SCOPUS

Title
Gold Nanoparticle Flow Sensors Designed for Dynamic X-ray Imaging in Biofluids
Authors
Ahn, SJung, SYLee, JPKim, HKLee, SJ
Date Issued
2010-07
Publisher
AMER CHEMICAL SOC
Abstract
X-ray-based imaging is one of the most powerful and convenient methods in terms of versatility in applicable energy and high performance in use. Different from conventional nuclear medicine imaging, contrast agents are required in X-ray imaging especially for effectively targeted and molecularly specific functions. Here, in contrast to much reported static accumulation of the contrast agents in targeted organs, dynamic visualization in a living organism is successfully accomplished by the particle-traced X-ray imaging for the first time. Flow phenomena across perforated end walls of xylem vessels in rice are monitored by a gold nanoparticle (AuNP) (similar to 20 nm in diameter) as a flow tracing sensor working in nontransparent biofluids. AuNPs are surface-modified to control the hydrodynamic properties such as hydrodynamic size (D-H), zeta-potential, and surface plasmonic properties in aqueous conditions. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray nanoscopy (XN), and X-ray microscopy (XM) are used to correlate the interparticle interactions with X-ray absorption ability. Cluster formation and X-ray contrast ability of the AuNPs are successfully modulated by controlling the interparticle interactions evaluated as flow-tracing sensors.
Keywords
dynamic X-ray imaging; gold nanoparticle (AuNP); contrast agents; smart materials; self-assembly; xylem vessel; sap flow; PLASMON RESONANCES; SPECTROSCOPY; PARTICLES; CONTRAST; ASCENT; XYLEM
URI
https://oasis.postech.ac.kr/handle/2014.oak/25454
DOI
10.1021/NN1003293
ISSN
1936-0851
Article Type
Article
Citation
ACS NANO, vol. 4, no. 7, page. 3753 - 3762, 2010-07
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이상준LEE, SANG JOON
Dept of Mechanical Enginrg
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