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Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2 '-deoxyuridines SCIE SCOPUS
- Title
- Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2 '-deoxyuridines
- Date Issued
- 2010-10-01
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- We have focused on the C5-modification of 2'-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate. (C) 2010 Elsevier Ltd. All rights reserved.
- Keywords
- Anticancer activity; 2 ' -Deoxyuridine; Perfluoroalkyltriazole; 1,3-Dipolar cycloaddition reaction; CANCER; ANALOGS; 5-FLUOROURACIL; CHEMOTHERAPY; FLUORINE
- ISSN
- 0960-894X
- Article Type
- Article
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 19, page. 5831 - 5834, 2010-10-01
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Related Researcher
- 김병현KIM, BYEANG HYEAN
- Div of Advanced Materials Science