DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, JY | - |
dc.contributor.author | Choi, JC | - |
dc.contributor.author | Shim, JH | - |
dc.contributor.author | Lee, JS | - |
dc.contributor.author | Park, H | - |
dc.contributor.author | Kim, SW | - |
dc.contributor.author | Doh, J | - |
dc.contributor.author | Cho, DW | - |
dc.date.accessioned | 2016-04-01T07:46:12Z | - |
dc.date.available | 2016-04-01T07:46:12Z | - |
dc.date.created | 2015-01-20 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 1758-5082 | - |
dc.identifier.other | 2014-OAK-0000033153 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/26852 | - |
dc.description.abstract | Bioprinting is a promising technique for engineering composite tissues, such as osteochondral tissues. In this study, as a first step toward bioprinting-based osteochondral tissue regeneration, we systematically examined the behavior of chondrocytes and osteoblasts to hyaluronic acid (HA) and type I collagen (Col-1) hydrogels. First, we demonstrated that cells on hydrogels that were comprised of major native tissue extracellular matrix (ECM) components (i.e. chondrocytes on HA hydrogels and osteoblasts on Col-1 hydrogels) exhibited better proliferation and cell function than cells on non-native ECM hydrogels (i.e., chondrocytes on Col-1 hydrogels and osteoblasts on HA hydrogels). In addition, cells located near their native ECM hydrogels migrated towards them. Finally, we bioprinted three-dimensional (3D) osteochondral tissue-mimetic structures composed of two compartments, osteoblast-encapsulated Col-1 hydrogels and chondrocyte-encapsulated HA hydrogels, and found viability and functions of each cell type were well maintained within the 3D structures up to 14 days in vitro. These results suggest that with proper choice of hydrogel materials, bioprinting-based approaches can be successfully applied for osteochondral tissue regeneration. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | IOP PUBLISHING LTD | - |
dc.relation.isPartOf | BIOFABRICATION | - |
dc.title | A comparative study on collagen type I and hyaluronic acid dependent cell behavior for osteochondral tissue bioprinting | - |
dc.type | Article | - |
dc.contributor.college | 기계공학과 | - |
dc.identifier.doi | 10.1088/1758-5082/6/3/035004 | - |
dc.author.google | Park, JY | - |
dc.author.google | Choi, JC | - |
dc.author.google | Shim, JH | - |
dc.author.google | Lee, JS | - |
dc.author.google | Park, H | - |
dc.author.google | Kim, SW | - |
dc.author.google | Doh, J | - |
dc.author.google | Cho, DW | - |
dc.relation.volume | 6 | - |
dc.relation.issue | 3 | - |
dc.contributor.id | 10189091 | - |
dc.relation.journal | BIOFABRICATION | - |
dc.relation.sci | SCIE | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOFABRICATION, v.6, no.3 | - |
dc.identifier.wosid | 000341823500004 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.number | 3 | - |
dc.citation.title | BIOFABRICATION | - |
dc.citation.volume | 6 | - |
dc.contributor.affiliatedAuthor | Doh, J | - |
dc.contributor.affiliatedAuthor | Cho, DW | - |
dc.identifier.scopusid | 2-s2.0-84899574160 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 56 | - |
dc.description.scptc | 48 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CARTILAGE | - |
dc.subject.keywordPlus | PROLIFERATION | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | BIOFABRICATION | - |
dc.subject.keywordPlus | DEGRADATION | - |
dc.subject.keywordPlus | FIBRONECTIN | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | MATRIX | - |
dc.subject.keywordAuthor | extracellular matrix | - |
dc.subject.keywordAuthor | bioprinting | - |
dc.subject.keywordAuthor | osteochondral tissue | - |
dc.subject.keywordAuthor | cell migration | - |
dc.subject.keywordAuthor | tissue engineering | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.