FABRICATION OF A HYDROXYAPATITE SCAFFOLD FOR BONE TISSUE REGENERATION USING MICROSTEREOLITHOGRAPHY AND MOLDING TECHNOLOGY

Abstract

Recently, many groups have researched the reconstruction of bone tissue and the development of bone scaffolds using solid freeform fabrication technology. However, the capacity to produce three-dimensional hydroxyapatite (HA) scaffolds with a very accurate architecture is limited by difficulties in the manufacturing process. In this study, a HA scaffold with an accurate pore size of 300 +/- 10 mu m was fabricated using a microstereolithography (MSTL) system and molding technology. In addition, an agar-overlay test was performed to investigate the cytotoxicity of the fabricated scaffold. (C) 2009 Elsevier B.V. All rights reserved.