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  Division of Advanced Materials Science (AMS) (첨단재료과학부) 1. Journal Papers

 

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Cited 102 time in webofscience Cited 108 time in scopus
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dc.contributor.authorLee, YS-
dc.contributor.authorPark, SM-
dc.contributor.authorKim, BH-
dc.date.accessioned2016-04-01T08:56:51Z-
dc.date.available2016-04-01T08:56:51Z-
dc.date.created2009-03-20-
dc.date.issued2009-02-15-
dc.identifier.issn0960-894X-
dc.identifier.other2009-OAK-0000011611-
dc.identifier.urihttps://oasis.postech.ac.kr/handle/2014.oak/29115-
dc.description.abstractThis paper describes a simple method for synthesizing a small library of 5-isoxazol-5-yl-2 '-deoxyuridines from 5-iodo-2 '-deoxyuridine. Nitrile oxides were generated in situ from oximes using a commercial bleaching agent; their cycloaddition with 5-ethynyl-2 '-deoxyuridine yielded isoxazoles possessing activity against herpes simplex viruses 1 and 2, Encephalomyocarditis virus, Coxsackie B3, and vesicular stomatitis virus; these isoxazoles were, however, inactive against corona virus, influenza virus, and HIV. (C) 2009 Published by Elsevier Ltd.-
dc.description.statementofresponsibilityX-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.subjectHSV-
dc.subjectAntiviral-
dc.subjectEMCV-
dc.subjectCox. B3-
dc.subjectVSV-
dc.subjectIsoxazole-
dc.subjectIsoxazole nucleosides-
dc.subjectAntiviral nucleoside-
dc.subject[3+2] Cycloaddition-
dc.subjectHERPES-SIMPLEX-VIRUS-
dc.subjectTHYMIDINE KINASE-
dc.subjectANALOGS-
dc.subjectISOXAZOLE-
dc.subjectTYPE-1-
dc.subjectCHEMOTHERAPY-
dc.subjectAFFINITY-
dc.subjectDESIGN-
dc.titleSynthesis of 5-isoxazol-5-yl-2 '-deoxyuridines exhibiting antiviral activity against HSV and several RNA viruses-
dc.typeArticle-
dc.contributor.college화학과-
dc.identifier.doi10.1016/j.bmcl.2008.12.103-
dc.author.googleLee, YS-
dc.author.googlePark, SM-
dc.author.googleKim, BH-
dc.relation.volume19-
dc.relation.issue4-
dc.relation.startpage1126-
dc.relation.lastpage1128-
dc.contributor.id10142056-
dc.relation.journalBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.relation.indexSCI급, SCOPUS 등재논문-
dc.relation.sciSCI-
dc.collections.nameJournal Papers-
dc.type.rimsART-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.19, no.4, pp.1126 - 1128-
dc.identifier.wosid000263295200019-
dc.date.tcdate2019-02-01-
dc.citation.endPage1128-
dc.citation.number4-
dc.citation.startPage1126-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume19-
dc.contributor.affiliatedAuthorKim, BH-
dc.identifier.scopusid2-s2.0-59649116011-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.wostc68-
dc.type.docTypeArticle-
dc.subject.keywordPlusHERPES-SIMPLEX-VIRUS-
dc.subject.keywordPlusTHYMIDINE KINASE-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordPlusISOXAZOLE-
dc.subject.keywordPlusTYPE-1-
dc.subject.keywordPlusCHEMOTHERAPY-
dc.subject.keywordPlusAFFINITY-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordAuthorHSV-
dc.subject.keywordAuthorAntiviral-
dc.subject.keywordAuthorEMCV-
dc.subject.keywordAuthorCox. B3-
dc.subject.keywordAuthorVSV-
dc.subject.keywordAuthorIsoxazole-
dc.subject.keywordAuthorIsoxazole nucleosides-
dc.subject.keywordAuthorAntiviral nucleoside-
dc.subject.keywordAuthor[3+2] Cycloaddition-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
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김병현KIM, BYEANG HYEAN
Div of Advanced Materials Science
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