DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeon, O | - |
dc.contributor.author | Song, SJ | - |
dc.contributor.author | Lee, KJ | - |
dc.contributor.author | Park, MH | - |
dc.contributor.author | Lee, SH | - |
dc.contributor.author | Hahn, SK | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Kim, BS | - |
dc.date.accessioned | 2016-04-01T09:06:59Z | - |
dc.date.available | 2016-04-01T09:06:59Z | - |
dc.date.created | 2009-03-05 | - |
dc.date.issued | 2007-10-01 | - |
dc.identifier.issn | 0144-8617 | - |
dc.identifier.other | 2007-OAK-0000010819 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/29483 | - |
dc.description.abstract | The effect of cross-linking density of hyaluronic acid (HA) hydrogels on mechanical properties and degradation behaviors has been investigated. HA hydrogels were prepared by the covalent cross-linking of HA with poly(ethylene glycol)-diamine with two different molecular weights at various cross-linking densities. The elastic modulus increased gradually as the theoretical cross-linking density of HA hydrogels increased from 0% to 20%. However, as the theoretical cross-linking density increased above 20%, the elastic modulus decreased. At a theoretical cross-linking density of 20%, the elastic modulus increased as the molecular weight of the cross-linking molecule decreased. In vitro degradation rates of HA hydrogels decreased as the molecular weight of the cross-linking molecule decreased at a theoretical cross-linking density of 20%. The degradation rate of the cross-linked HA hydrogels decreased with increases in the theoretical cross-linking density from 0% to 20%. However, there was no significant difference in the degradation rate as the theoretical cross-linking density increased above 30%. With controllable mechanical properties and degradation rates, the developed HA hydrogels would be further investigated for various medical applications. (c) 2007 Elsevier Ltd. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.relation.isPartOf | CARBOHYDRATE POLYMERS | - |
dc.subject | cross-linking | - |
dc.subject | degradation | - |
dc.subject | elastic modulus | - |
dc.subject | hyaluronic acid | - |
dc.subject | hydrogel | - |
dc.subject | poly(ethylene glycol) | - |
dc.subject | FIBROBLAST-GROWTH-FACTOR | - |
dc.subject | FUNCTIONALIZED DERIVATIVES | - |
dc.subject | FIBRIN MATRIX | - |
dc.subject | TRANSPLANTATION | - |
dc.subject | BIOMATERIALS | - |
dc.subject | RIGIDITY | - |
dc.subject | ALGINATE | - |
dc.subject | RELEASE | - |
dc.subject | FILMS | - |
dc.title | Mechanical properties and degradation behaviors of hyaluronic acid hydrogels cross-linked at various cross-linking densities | - |
dc.type | Article | - |
dc.contributor.college | 신소재공학과 | - |
dc.identifier.doi | 10.1016/j.carbpol.2007.04.002 | - |
dc.author.google | Jeon, O | - |
dc.author.google | Song, SJ | - |
dc.author.google | Lee, KJ | - |
dc.author.google | Park, MH | - |
dc.author.google | Lee, SH | - |
dc.author.google | Hahn, SK | - |
dc.author.google | Kim, S | - |
dc.author.google | Kim, BS | - |
dc.relation.volume | 70 | - |
dc.relation.issue | 3 | - |
dc.relation.startpage | 251 | - |
dc.relation.lastpage | 257 | - |
dc.contributor.id | 10149037 | - |
dc.relation.journal | CARBOHYDRATE POLYMERS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CARBOHYDRATE POLYMERS, v.70, no.3, pp.251 - 257 | - |
dc.identifier.wosid | 000250257600001 | - |
dc.citation.endPage | 257 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 251 | - |
dc.citation.title | CARBOHYDRATE POLYMERS | - |
dc.citation.volume | 70 | - |
dc.contributor.affiliatedAuthor | Hahn, SK | - |
dc.contributor.affiliatedAuthor | Kim, S | - |
dc.identifier.scopusid | 2-s2.0-34548502425 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | FUNCTIONALIZED DERIVATIVES | - |
dc.subject.keywordPlus | TRANSPLANTATION | - |
dc.subject.keywordPlus | RIGIDITY | - |
dc.subject.keywordPlus | ALGINATE | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordAuthor | cross-linking | - |
dc.subject.keywordAuthor | degradation | - |
dc.subject.keywordAuthor | elastic modulus | - |
dc.subject.keywordAuthor | hyaluronic acid | - |
dc.subject.keywordAuthor | hydrogel | - |
dc.subject.keywordAuthor | poly(ethylene glycol) | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
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