Quencher-free molecular aptamer beacons (QF-MABs) for detection of ATP
SCIE
SCOPUS
- Title
- Quencher-free molecular aptamer beacons (QF-MABs) for detection of ATP
- Authors
- Park, JW; Park, Y; Kim, BH
- Date Issued
- 2015-10-15
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- We have constructed a simple and efficient system-based on quencher-free molecular aptamer beacons (QF-MABs)-for probing ATP. In the absence of ATP, the fluorescence of a pyrene fluorophore on the loop position (15 nucleotides from the 5' end) of the optimal QF-MAB was quenched by the neighboring nucleobases; in its presence, fluorescence was recovered, due to a conformational change in the secondary structure of the QF-MAB. (C) 2015 Elsevier Ltd. All rights reserved.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/35456
- DOI
- 10.1016/J.BMCL.2015.08.052
- ISSN
- 0960-894X
- Article Type
- Article
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, no. 20, page. 4597 - 4600, 2015-10-15
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