DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, YJ | - |
dc.contributor.author | Kim, TG | - |
dc.contributor.author | Jeong, J | - |
dc.contributor.author | Yi, HG | - |
dc.contributor.author | Park, JW | - |
dc.contributor.author | Hwang, W | - |
dc.contributor.author | Cho, DW | - |
dc.date.accessioned | 2017-07-19T13:27:06Z | - |
dc.date.available | 2017-07-19T13:27:06Z | - |
dc.date.created | 2017-02-03 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/36995 | - |
dc.description.abstract | Engineered skeletal muscle tissues that mimic the structure and function of native muscle have been considered as an alternative strategy for the treatment of various muscular diseases and injuries. Here, it is demonstrated that 3D cell-printing of decellularized skeletal muscle extracellular matrix (mdECM)-based bioink facilitates the fabrication of functional skeletal muscle constructs. The cellular alignment and the shape of the tissue constructs are controlled by 3D cell-printing technology. mdECM bioink provides the 3D cell-printed muscle constructs with a myogenic environment that supports high viability and contractility as well as myotube formation, differentiation, and maturation. More interestingly, the preservation of agrin is confirmed in the mdECM, and significant increases in the formation of acetylcholine receptor clusters are exhibited in the 3D cell-printed muscle constructs. In conclusion, mdECM bioink and 3D cell-printing technology facilitate the mimicking of both the structural and functional properties of native muscle and hold great promise for producing clinically relevant engineered muscle for the treatment of muscular injuries. | - |
dc.language | English | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.relation.isPartOf | ADVANCED HEALTHCARE MATERIALS | - |
dc.title | 3D Cell Printing of Functional Skeletal Muscle Constructs Using Skeletal Muscle-Derived Bioink | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/adhm.201600483 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ADVANCED HEALTHCARE MATERIALS, v.5, no.20, pp.2636 - 2645 | - |
dc.identifier.wosid | 000387158900005 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 2645 | - |
dc.citation.number | 20 | - |
dc.citation.startPage | 2636 | - |
dc.citation.title | ADVANCED HEALTHCARE MATERIALS | - |
dc.citation.volume | 5 | - |
dc.contributor.affiliatedAuthor | Hwang, W | - |
dc.contributor.affiliatedAuthor | Cho, DW | - |
dc.identifier.scopusid | 2-s2.0-84981730963 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 35 | - |
dc.description.scptc | 22 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | EXTRACELLULAR-MATRIX | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | GEOMETRY | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordAuthor | 3D cell-printing technology | - |
dc.subject.keywordAuthor | bioink | - |
dc.subject.keywordAuthor | decellularized extracellular matrix | - |
dc.subject.keywordAuthor | engineered muscle constructs | - |
dc.subject.keywordAuthor | skeletal muscles | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.