DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, BY | - |
dc.contributor.author | hyun Seung | - |
dc.contributor.author | Jeon, G | - |
dc.contributor.author | Eun Young Kim | - |
dc.contributor.author | Kim, J | - |
dc.contributor.author | Kim, WJ | - |
dc.contributor.author | Kim, JR | - |
dc.date.accessioned | 2017-07-19T13:27:31Z | - |
dc.date.available | 2017-07-19T13:27:31Z | - |
dc.date.created | 2017-02-02 | - |
dc.date.issued | 2016-05-11 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/37012 | - |
dc.description.abstract | Stimuli-responsive polymers have been widely used for controlled release of several biomolecules. In general, a single stimulus among various stimuli, for instance, temperature, pH, or light, has been used for these polymers. Although some stimuli are applied together, one cannot control each stimulus independently at a given stimulus-responsive polymer. However, to mimic biological system like cell membrane, multiple on off gates utilizing independent control of dual (or multiple) stimuli should be used. Here, we introduce a stimuli-responsive membrane controlled by two orthogonal stimuli. For this purpose, the top and the bottom parts of anodized aluminum oxide membrane walls are independently grafted by thermoresponsive poly(N-isopropylacrylamide) and pH-responsive poly(acrylic acid), respectively, by using surface-initiated atom transfer radical polymerization. The membrane clearly showed two independent on off gates depending on temperature and pH. Furthermore, through light irradiation of two different wavelengths (near-infrared and ultraviolet), temperature and pH were also controlled independently and promptly. Thus, this membrane shows two independent on-off gating of the transport of a model biomolecule of fluorescein isothiocyanate-labeled bovine serum albumin. This strategy suggests the potential of independently modified membrane in layers as stimuli-responsive on off gates for the application of artificial cell membrane. | - |
dc.language | English | - |
dc.publisher | ACS Publications | - |
dc.relation.isPartOf | ACS Applied Mater.Inter | - |
dc.title | Bioinspired Dual Stimuli-Responsive Membranous System with Multiple On–Off Gates | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/ACSAMI.6B01788 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ACS Applied Mater.Inter, v.8, no.18, pp.11758 - 11764 | - |
dc.identifier.wosid | 000375521000065 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 11764 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 11758 | - |
dc.citation.title | ACS Applied Mater.Inter | - |
dc.citation.volume | 8 | - |
dc.contributor.affiliatedAuthor | Lee, BY | - |
dc.contributor.affiliatedAuthor | Kim, J | - |
dc.contributor.affiliatedAuthor | Kim, WJ | - |
dc.identifier.scopusid | 2-s2.0-84974604983 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 11 | - |
dc.description.scptc | 6 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CONTROLLED-RELEASE | - |
dc.subject.keywordPlus | POLYMERS | - |
dc.subject.keywordPlus | POLY(N-ISOPROPYLACRYLAMIDE) | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | HYDROGEL | - |
dc.subject.keywordPlus | STATE | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | GLOBULE | - |
dc.subject.keywordPlus | ACID) | - |
dc.subject.keywordAuthor | artificial cell membrane | - |
dc.subject.keywordAuthor | biomimetics | - |
dc.subject.keywordAuthor | hybrid materials | - |
dc.subject.keywordAuthor | stimuli-responsive materials | - |
dc.subject.keywordAuthor | surface modification | - |
dc.subject.keywordAuthor | spatiotemporal and prompt gating | - |
dc.subject.keywordAuthor | on-off gating | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
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