DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nari Kim | - |
dc.contributor.author | Hesung Now | - |
dc.contributor.author | Nguyen Thi Hong Nhung | - |
dc.contributor.author | Yoo, JY | - |
dc.date.accessioned | 2017-07-19T13:43:05Z | - |
dc.date.available | 2017-07-19T13:43:05Z | - |
dc.date.created | 2016-09-09 | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 1225-8873 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/37448 | - |
dc.description.abstract | RIG-I is a cytosolic receptor recognizing virus-specific RNA structures and initiates an antiviral signaling that induces the production of interferons and proinflammatory cytokines. Because inappropriate RIG-I signaling affects either viral clearance or immune toxicity, multiple regulations of RIG-I have been investigated since its discovery as the viral RNA detector. In this review, we describe the recent progress in research on the regulation of RIG-I activity or abundance. Specifically, we focus on the mechanism that modulates RIGI- dependent antiviral response through post-translational modifications of or protein-protein interactions with RIG-I. | - |
dc.language | English | - |
dc.publisher | Seoul : Microbiological Society Of Korea | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY | - |
dc.title | Multilayered regulations of RIG-I in the anti-viral signaling pathway | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/S12275-016-6322-2 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY, v.54, no.9, pp.583 - 587 | - |
dc.identifier.kciid | ART002134809 | - |
dc.identifier.wosid | 000382411700001 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 587 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 583 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY | - |
dc.citation.volume | 54 | - |
dc.contributor.affiliatedAuthor | Nari Kim | - |
dc.contributor.affiliatedAuthor | Yoo, JY | - |
dc.identifier.scopusid | 2-s2.0-84984656825 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 5 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Review | - |
dc.subject.keywordPlus | INNATE IMMUNE-RESPONSE | - |
dc.subject.keywordPlus | E3 UBIQUITIN LIGASE | - |
dc.subject.keywordPlus | INTERFERON INDUCTION | - |
dc.subject.keywordPlus | VIRUS-INFECTION | - |
dc.subject.keywordPlus | VIRAL-RNA | - |
dc.subject.keywordPlus | NEGATIVE REGULATION | - |
dc.subject.keywordPlus | STRUCTURAL BASIS | - |
dc.subject.keywordPlus | PROTEIN-KINASE | - |
dc.subject.keywordPlus | PHOSPHORYLATION | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordAuthor | RIG-I | - |
dc.subject.keywordAuthor | antiviral signaling | - |
dc.subject.keywordAuthor | RNA virus | - |
dc.subject.keywordAuthor | post-translational modification | - |
dc.subject.keywordAuthor | protein-protein interaction | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Microbiology | - |
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