DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lloyd M. Davis | - |
dc.contributor.author | Frederic R. Fairfield | - |
dc.contributor.author | Carol A. Harger | - |
dc.contributor.author | James H. Jett | - |
dc.contributor.author | Richard A. Keller | - |
dc.contributor.author | Jong Hoon Hahn | - |
dc.contributor.author | Letitia A. Krakowski | - |
dc.contributor.author | Babetta L. Marrone | - |
dc.contributor.author | John C. Martin | - |
dc.contributor.author | Harvey L. Nutter | - |
dc.contributor.author | Robert L. Ratliff | - |
dc.contributor.author | E. Brooks Shera | - |
dc.contributor.author | Daniel J. Simpson | - |
dc.contributor.author | Steven A. Soper | - |
dc.date.accessioned | 2018-01-08T11:09:00Z | - |
dc.date.available | 2018-01-08T11:09:00Z | - |
dc.date.created | 2009-03-26 | - |
dc.date.issued | 1991-02 | - |
dc.identifier.issn | 1050-3862 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/40085 | - |
dc.description.abstract | We are developing a laser-based technique for the rapid sequencing of 40-kb or larger fragments of DNA at a rate of 100 to 1000 bases per second. The approach relies on fluorescent labeling of the bases in a single fragment of DNA, attachment of this labeled DNA fragment to a support, movement of the supported DNA fragment into a flowing sample stream, and detection of individual fluorescently labeled bases as they are cleaved from the DNA fragment by an exonuclease. The ability to sequence large fragments of DNA will significantly reduce the amount of subcloning and the number of overlapping sequences required to assemble megabase segments of sequence information. | - |
dc.language | English | - |
dc.publisher | ELSEVIER BV | - |
dc.relation.isPartOf | GENETIC ANALYSIS TECHNIQUES AND APPLICATIONS | - |
dc.title | RAPID DNA SEQUENCING BASED UPON SINGLE MOLECULE DETECTION | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/1050-3862(91)90002-9 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | GENETIC ANALYSIS TECHNIQUES AND APPLICATIONS, v.8, no.1, pp.1 - 7 | - |
dc.identifier.wosid | A1991FG99200001 | - |
dc.citation.endPage | 7 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.title | GENETIC ANALYSIS TECHNIQUES AND APPLICATIONS | - |
dc.citation.volume | 8 | - |
dc.contributor.affiliatedAuthor | Jong Hoon Hahn | - |
dc.identifier.scopusid | 2-s2.0-0025894177 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.scptc | 46 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | LASER-INDUCED FLUORESCENCE | - |
dc.subject.keywordPlus | SAMPLES | - |
dc.subject.keywordPlus | PROCESSIVITY | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Genetics & Heredity | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Genetics & Heredity | - |
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