Transition Metal-mediated/catalyzed Fluorination Methodology Developed in the 2000s

Abstract

In the 2000s, there has been a significant advance on carbon–fluorine (C–F) bond formation reactions via transition metal mediated or catalyzed methods. Of course, for the past 10 years, transition metal catalysis improves C-F bond formation in terms of practicality and even can be applied to C-18F bond formation reaction. In this mini-review, we summarize various transition metal mediated or catalyzed fluorination reactions, which were developed in the mid-2000s.