DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sangsoon Park | - |
dc.contributor.author | Yoonji Jung | - |
dc.contributor.author | Seon Woo A. An | - |
dc.contributor.author | Heehwa G. Son | - |
dc.contributor.author | Wooseon Hwang | - |
dc.contributor.author | Dongyeop Lee | - |
dc.contributor.author | Murat Artan | - |
dc.contributor.author | Hae-Eun H. Park, | - |
dc.contributor.author | Dae-Eun Jeong | - |
dc.contributor.author | Seung-Jae V. Lee | - |
dc.date.accessioned | 2018-05-03T09:37:58Z | - |
dc.date.available | 2018-05-03T09:37:58Z | - |
dc.date.created | 2018-02-07 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 2046-1402 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/41048 | - |
dc.description.abstract | Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization. Methods: Here, we sought to examine the roles of α-arrestins in the longevity of Caenorhabditis elegans through an RNA interference screen. Results: We found that feeding worms with bacteria expressing double-stranded RNA against each of 24 out of total 29 C. elegans α-arrestins had little effect on lifespan. Thus, individual C. elegans α-arrestins may have minor effects on longevity. Conclusions: This study will provide useful information for future research on the functional role of α-arrestins in aging and longevity. | - |
dc.language | English | - |
dc.publisher | F1000Research 2017 | - |
dc.relation.isPartOf | F1000Research | - |
dc.title | RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan | - |
dc.type | Article | - |
dc.identifier.doi | 10.12688/f1000research.12337.2 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | F1000Research, v.6, no.1515 | - |
dc.citation.number | 1515 | - |
dc.citation.title | F1000Research | - |
dc.citation.volume | 6 | - |
dc.contributor.affiliatedAuthor | Sangsoon Park | - |
dc.contributor.affiliatedAuthor | Yoonji Jung | - |
dc.contributor.affiliatedAuthor | Seon Woo A. An | - |
dc.contributor.affiliatedAuthor | Heehwa G. Son | - |
dc.contributor.affiliatedAuthor | Wooseon Hwang | - |
dc.contributor.affiliatedAuthor | Dongyeop Lee | - |
dc.contributor.affiliatedAuthor | Murat Artan | - |
dc.contributor.affiliatedAuthor | Hae-Eun H. Park, | - |
dc.contributor.affiliatedAuthor | Dae-Eun Jeong | - |
dc.contributor.affiliatedAuthor | Seung-Jae V. Lee | - |
dc.identifier.scopusid | 2-s2.0-85032984087 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Aging | - |
dc.subject.keywordAuthor | C. elegans | - |
dc.subject.keywordAuthor | Insulin/IGF-1 signaling | - |
dc.subject.keywordAuthor | Lifespan | - |
dc.subject.keywordAuthor | ��-arrestin | - |
dc.description.journalRegisteredClass | scopus | - |
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