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Luciferase-Rose Bengal Conjugates for Single Oxygen Generation by Bioluminescence Resonant Energy Transfer SCIE SCOPUS
- Title
- Luciferase-Rose Bengal Conjugates for Single Oxygen Generation by Bioluminescence Resonant Energy Transfer
- Authors
- Kim, Seonghoon; Jo, HyeongChan; Jeon, Mijeong; Choi, Myung-Gyu; HAHN, SEI KWANG; Yun, Seok-Hyun
- Date Issued
- 2017-03
- Publisher
- Royal Society of Chemistry
- Abstract
- Conjugates of Rose Bengal and Renilla luciferase generated singlet oxygen upon binding with coelenterazine via bioluminescence resonance energy transfer (BRET). Since the applications of conventional PDT have been limited to superficial lesions due to the limited light penetration in tissue, BRET activated PDT which does not require external light illumination may overcome the limitations of conventional PDT.
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- Chemical Communications, vol. 53, 2017-03
- Files in This Item:
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Related Researcher
- 한세광HAHN, SEI KWANG
- Dept of Materials Science & Enginrg