DC Field | Value | Language |
---|---|---|
dc.contributor.author | Marino, Attilio | - |
dc.contributor.author | Arai, Satoshi | - |
dc.contributor.author | Hou, Yanyan | - |
dc.contributor.author | Sinibaldi, Edoardo | - |
dc.contributor.author | Pellegrino, Mario | - |
dc.contributor.author | Chang, Young-Tae | - |
dc.contributor.author | Mazzolai, Barbara | - |
dc.contributor.author | Mattoli, Virgilio | - |
dc.contributor.author | Suzuki, Madoka | - |
dc.contributor.author | Ciofani, Gianni | - |
dc.date.accessioned | 2018-06-15T05:16:02Z | - |
dc.date.available | 2018-06-15T05:16:02Z | - |
dc.date.created | 2017-09-08 | - |
dc.date.issued | 2015-07 | - |
dc.identifier.issn | 1936-0851 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/50279 | - |
dc.description.abstract | Tetragonal barium titanate nanoparticles (BTNPs) have been exploited as nanotransducers owing to their piezoelectric properties, in order to provide indirect electrical stimulation to SH-SY5Y neuron-like cells. Following application of ultrasounds to cells treated with BTNPs, fluorescence imaging of ion dynamics revealed that the synergic stimulation is able to elicit a significant cellular response in terms of calcium and sodium fluxes; moreover, tests with appropriate blockers demonstrated that voltage-gated membrane channels are activated. The hypothesis of piezoelectric stimulation of neuron-like cells was supported by lack of cellular response in the presence of cubic nonpiezoelectric BTNPs, and further corroborated by a simple electroelastic model of a BTNP subjected to ultrasounds, according to which the generated voltage is compatible with the values required for the activation of voltage-sensitive channels. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.relation.isPartOf | ACS NANO | - |
dc.subject | BARIUM-TITANATE NANOPARTICLES | - |
dc.subject | GATED ION CHANNELS | - |
dc.subject | NEURITE OUTGROWTH | - |
dc.subject | BRAIN-STIMULATION | - |
dc.subject | ELECTROSPUN SCAFFOLDS | - |
dc.subject | ENDOPLASMIC-RETICULUM | - |
dc.subject | CATION CHANNELS | - |
dc.subject | LEECH NEURONS | - |
dc.subject | TEMPERATURE | - |
dc.subject | ULTRASOUND | - |
dc.title | Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acsnano.5b03162 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | ACS NANO, v.9, no.7, pp.7678 - 7689 | - |
dc.identifier.wosid | 000358823200105 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 7689 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 7678 | - |
dc.citation.title | ACS NANO | - |
dc.citation.volume | 9 | - |
dc.contributor.affiliatedAuthor | Chang, Young-Tae | - |
dc.identifier.scopusid | 2-s2.0-84938151046 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 43 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | BARIUM-TITANATE NANOPARTICLES | - |
dc.subject.keywordPlus | GATED ION CHANNELS | - |
dc.subject.keywordPlus | NEURITE OUTGROWTH | - |
dc.subject.keywordPlus | BRAIN-STIMULATION | - |
dc.subject.keywordPlus | ELECTROSPUN SCAFFOLDS | - |
dc.subject.keywordPlus | ENDOPLASMIC-RETICULUM | - |
dc.subject.keywordPlus | CATION CHANNELS | - |
dc.subject.keywordPlus | LEECH NEURONS | - |
dc.subject.keywordPlus | TEMPERATURE | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordAuthor | barium titanate nanoparticles | - |
dc.subject.keywordAuthor | ultrasounds | - |
dc.subject.keywordAuthor | piezoelectricity | - |
dc.subject.keywordAuthor | SH-SY5Y cells | - |
dc.subject.keywordAuthor | calcium imaging | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
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