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A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation SCIE SCOPUS
- Title
- A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation
- Authors
- Yun, Seong-Wook; Leong, Cheryl; Bi, Xuezhi; Ha, Hyung-Ho; Yu, Yuan Hong; Tan, Yee Ling; Narayanan, Gunaseelan; Sankaran, Shvetha; Kim, Jun-Young; Hariharan, Srivats; Ahmed, Sohail; Chang, Young-Tae
- Date Issued
- 2014
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- We report here a novel fluorescent chemical probe CDy5 which stains distinct neural stem/progenitor cells (NSPCs) by binding to acid ceramidase in mouse neurospheres. CDy5 is distributed evenly or unevenly to the daughter cells during multiple mitoses enabling the live imaging of symmetric and asymmetric divisions of isolated NSPCs.
- Keywords
- HUMAN ACID CERAMIDASE; STEM-CELLS; CANCER; DISEASE; INHIBITORS; DISCOVERY; SURVIVAL; CLONING
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 50, no. 56, page. 7492 - 7494, 2014
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Related Researcher
- 장영태CHANG, YOUNG TAE
- Dept of Chemistry