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A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue SCIE SCOPUS

Title
A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue
Authors
Zhai, DuantingLee, Sung-ChanYunb, Seong-WookChang, Young-Tae
Date Issued
2013
Publisher
ROYAL SOC CHEMISTRY
Abstract
A novel ratiometric biothiol probe Glutathione Green was developed. It allows quantitative measurement of glutathione in cell extracts and direct visualization of changes in glutathione levels in live cells. Remarkably, this is the first reported biothiol probe which can detect the carcinoma region of liver tissue based on the differences in the glutathione level.
Keywords
HUMAN HEPATOCELLULAR-CARCINOMA; SOLID-PHASE SYNTHESIS; PROBE DEVELOPMENT; BODIPY LIBRARY; IMAGING PROBE; SENSOR; THIOLS; MECHANISM; BOND
URI
https://oasis.postech.ac.kr/handle/2014.oak/50328
DOI
10.1039/c3cc43480j
ISSN
1359-7345
Article Type
Article
Citation
CHEMICAL COMMUNICATIONS, vol. 49, no. 65, page. 7207 - 7209, 2013
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