A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue
SCIE
SCOPUS
- Title
- A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue
- Authors
- Zhai, Duanting; Lee, Sung-Chan; Yunb, Seong-Wook; Chang, Young-Tae
- Date Issued
- 2013
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- A novel ratiometric biothiol probe Glutathione Green was developed. It allows quantitative measurement of glutathione in cell extracts and direct visualization of changes in glutathione levels in live cells. Remarkably, this is the first reported biothiol probe which can detect the carcinoma region of liver tissue based on the differences in the glutathione level.
- Keywords
- HUMAN HEPATOCELLULAR-CARCINOMA; SOLID-PHASE SYNTHESIS; PROBE DEVELOPMENT; BODIPY LIBRARY; IMAGING PROBE; SENSOR; THIOLS; MECHANISM; BOND
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/50328
- DOI
- 10.1039/c3cc43480j
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 49, no. 65, page. 7207 - 7209, 2013
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- There are no files associated with this item.
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