Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogues
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SCOPUS
- Title
- Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogues
- Authors
- Wang, Shenliang; Lee, Woo Sirl; Ha, Hyung-Ho; Chang, Young-Tae
- Date Issued
- 2011
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- Herein we report a parallel solid-phase synthesis of 1,3,5-triazine based nucleoside analogues by a three-step substitution, starting from 2,4,6-trichloro-1,3,5-triazine. A library of 80 galactosyl-1,3,5-triazine compounds was prepared in high purity without extensive reaction conditions or tedious purification, suggesting the generality of this method.
- Keywords
- TRIAZINE LIBRARY; ANTAGONISTS; THERAPY
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/50351
- DOI
- 10.1039/c1ob05733b
- ISSN
- 1477-0520
- Article Type
- Article
- Citation
- ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, no. 20, page. 6924 - 6926, 2011
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