DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ramya, A. N. | - |
dc.contributor.author | Samanta, Animesh | - |
dc.contributor.author | Nisha, N. | - |
dc.contributor.author | Chang, Young-Tae | - |
dc.contributor.author | Maiti, Kaustabh Kumar | - |
dc.date.accessioned | 2018-06-15T05:21:25Z | - |
dc.date.available | 2018-06-15T05:21:25Z | - |
dc.date.created | 2017-09-08 | - |
dc.date.issued | 2015-02 | - |
dc.identifier.issn | 1743-5889 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/50393 | - |
dc.description.abstract | Aim: Development of highly sensitive diagnostic nanoprobe for cancer imaging based on surface-enhanced Raman scattering (SERS) platform. Materials & methods: Synthesis of novel squaraine dyes as a Raman signature molecule denoted as lipoic-squaraine-lipoic (LSL), propyl-squaraine-lipoic (PSL) and propyl-squaraine-propyl (PSP). The SERS-nanotag constructed with a Raman signature molecule which is attached on gold nanoparticle and further encapsulated with heterofunctionalized PEG. Antibody conjugation with best SERS-nanotag for target specific recognition. Results: SERS nanotag Au-LSL-PEG showed significant signal intensity and remarkable stability. Anti-EGF receptor and Her2-conjugated Au-LSL-PEG-nanotag were successfully applied for selective recognition of cancer cells like A549, OSCC and MCF7. Conclusion: The newly developed SERS-nanotag Au-LSL-PEG serves as a valuable tool for diagnostic detection of cancer cells, and may find potential applications for cancer screening in real patient samples. | - |
dc.language | English | - |
dc.publisher | FUTURE MEDICINE LTD | - |
dc.relation.isPartOf | NANOMEDICINE | - |
dc.title | New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging | - |
dc.type | Article | - |
dc.identifier.doi | 10.2217/nnm.14.125 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | NANOMEDICINE, v.10, no.4, pp.561 - 571 | - |
dc.identifier.wosid | 000350583800004 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 571 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 561 | - |
dc.citation.title | NANOMEDICINE | - |
dc.citation.volume | 10 | - |
dc.contributor.affiliatedAuthor | Chang, Young-Tae | - |
dc.identifier.scopusid | 2-s2.0-84924154640 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 10 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordPlus | DYE | - |
dc.subject.keywordPlus | PROBES | - |
dc.subject.keywordPlus | SERRS | - |
dc.subject.keywordPlus | GOLD | - |
dc.subject.keywordPlus | TAGS | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordAuthor | antibody conjugation | - |
dc.subject.keywordAuthor | cancer screening | - |
dc.subject.keywordAuthor | Raman signature molecule | - |
dc.subject.keywordAuthor | SERS | - |
dc.subject.keywordAuthor | squaraine dye | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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