DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhang, Lijun | - |
dc.contributor.author | Wang, Guiheng | - |
dc.contributor.author | Xiong, Can | - |
dc.contributor.author | Zheng, Lei | - |
dc.contributor.author | He, Jianbo | - |
dc.contributor.author | Ding, Yunsheng | - |
dc.contributor.author | Lu, Hongbo | - |
dc.contributor.author | Zhang, Guobing | - |
dc.contributor.author | Cho, Kilwon | - |
dc.contributor.author | Qiu, Longzhen | - |
dc.date.accessioned | 2018-06-15T05:46:13Z | - |
dc.date.available | 2018-06-15T05:46:13Z | - |
dc.date.created | 2018-03-19 | - |
dc.date.issued | 2018-05 | - |
dc.identifier.issn | 0956-5663 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/50825 | - |
dc.description.abstract | Chiral recognition of alpha-amino acids is attracting increasing interest due to the importance of alpha-amino acids in protein metabolism as well as in food products and pharmaceuticals. Organic electrochemical transistors (OECTs) with gate electrodes modified with molecularly imprinted polymer (MIP) films were fabricated and successfully used as highly selective and sensitive chiral recognition biosensors for D/L-tryptophan (D/L-Trp) and D/L-tyrosine (D/L-Tyr). The MIP films, which can specifically recognize and has an electrocatalytic effect on the oxidation of Trp and Tyr, together with the amplification function of an OECT, provide a highly sensitive and selective OECT biosensor. The sensor showed a linear response range for L-Trp and t-Tyr from 300 nM to 10 mu M with a sensitivity of 3.19 and 3.64 mu A/mu M, respectivity. And the detection limit for L-Trp and L-Tyr is of 2 nM and 30 nM (S/N > 3). The selectivity factors of L-Trp, D-Trp, L-Tyr and D-Tyr to their enantiomers are 11.6, 3.5, 14.5 and 2.6, respectively. This method can pave the way for widespread applications of OECT-based sensors in chiral material identification. | - |
dc.language | English | - |
dc.publisher | ELSEVIER ADVANCED TECHNOLOGY | - |
dc.relation.isPartOf | BIOSENSORS & BIOELECTRONICS | - |
dc.subject | MODIFIED GATE ELECTRODES | - |
dc.subject | CARBON-PASTE ELECTRODE | - |
dc.subject | ENANTIOSELECTIVE RECOGNITION | - |
dc.subject | L-TRYPTOPHAN | - |
dc.subject | GLUCOSE SENSORS | - |
dc.subject | L-TYROSINE | - |
dc.subject | POLYPYRROLE | - |
dc.subject | BIOSENSORS | - |
dc.subject | FILMS | - |
dc.subject | PHENYLALANINE | - |
dc.title | Chirality detection of amino acid enantiomers by organic electrochemical transistor | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.bios.2018.01.035 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOSENSORS & BIOELECTRONICS, v.105, pp.121 - 128 | - |
dc.identifier.wosid | 000426024200019 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 128 | - |
dc.citation.startPage | 121 | - |
dc.citation.title | BIOSENSORS & BIOELECTRONICS | - |
dc.citation.volume | 105 | - |
dc.contributor.affiliatedAuthor | Cho, Kilwon | - |
dc.identifier.scopusid | 2-s2.0-85041375498 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 4 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | MODIFIED GATE ELECTRODES | - |
dc.subject.keywordPlus | CARBON-PASTE ELECTRODE | - |
dc.subject.keywordPlus | ENANTIOSELECTIVE RECOGNITION | - |
dc.subject.keywordPlus | L-TRYPTOPHAN | - |
dc.subject.keywordPlus | GLUCOSE SENSORS | - |
dc.subject.keywordPlus | L-TYROSINE | - |
dc.subject.keywordPlus | POLYPYRROLE | - |
dc.subject.keywordPlus | BIOSENSORS | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordPlus | PHENYLALANINE | - |
dc.subject.keywordAuthor | Chiral recognition biosensors | - |
dc.subject.keywordAuthor | Organic electrochemical transistors | - |
dc.subject.keywordAuthor | Molecularly imprinted polymers | - |
dc.subject.keywordAuthor | Electro-catalysis | - |
dc.subject.keywordAuthor | Tryptophan and tyrosine | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
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