DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwang, AB | - |
dc.contributor.author | Lee, SJ | - |
dc.date.accessioned | 2015-06-23T07:01:07Z | - |
dc.date.available | 2015-06-23T07:01:07Z | - |
dc.date.created | 2011-05-16 | - |
dc.date.issued | 2011-03 | - |
dc.identifier.issn | 1945-4589 | - |
dc.identifier.other | 2015-OAK-0000023520 | en_US |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/9296 | - |
dc.description.abstract | A mild reduction in mitochondrial respiration extends the life span of many species, including C. elegans. We recently showed that hypoxia-inducible factor 1 (HIF-1) is required for the acquisition of a long life span by mutants with reduced respiration in C. elegans. We suggested that increased levels of reactive oxygen species (ROS) produced in the respiration mutants increase HIF-1 activity and lead to this longevity. In this research perspective, we discuss our findings and recent advances regarding the roles of ROS and HIF-1 in aging, focusing on the longevity caused by reduced respiration. | - |
dc.description.statementofresponsibility | open | en_US |
dc.language | English | - |
dc.publisher | IMPACT JOURNALS LLC | - |
dc.relation.isPartOf | AGING-US | - |
dc.rights | BY_NC_ND | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.0/kr | en_US |
dc.title | Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection | - |
dc.type | Article | - |
dc.contributor.college | 정보전자융합공학부 | en_US |
dc.identifier.doi | 10.18632/aging.100292 | - |
dc.author.google | Hwang, AB | en_US |
dc.author.google | Lee, SJ | en_US |
dc.relation.volume | 3 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.startpage | 304 | en_US |
dc.relation.lastpage | 310 | en_US |
dc.contributor.id | 10201212 | en_US |
dc.relation.journal | AGING-US | en_US |
dc.relation.index | SCI급, SCOPUS 등재논문 | en_US |
dc.relation.sci | SCIE | en_US |
dc.collections.name | Journal Papers | en_US |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | AGING-US, v.3, no.3, pp.304 - 310 | - |
dc.identifier.wosid | 000289311900013 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 310 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 304 | - |
dc.citation.title | AGING-US | - |
dc.citation.volume | 3 | - |
dc.contributor.affiliatedAuthor | Lee, SJ | - |
dc.identifier.scopusid | 2-s2.0-80051647245 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 45 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | NEMATODE CAENORHABDITIS-ELEGANS | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | C-ELEGANS | - |
dc.subject.keywordPlus | ELECTRON-TRANSPORT | - |
dc.subject.keywordPlus | ENERGY-METABOLISM | - |
dc.subject.keywordPlus | COMPLEX-III | - |
dc.subject.keywordPlus | STEM-CELLS | - |
dc.subject.keywordPlus | HYPOXIA | - |
dc.subject.keywordPlus | MUTANTS | - |
dc.subject.keywordPlus | DYSFUNCTION | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Geriatrics & Gerontology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Geriatrics & Gerontology | - |
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