DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, In Su | - |
dc.contributor.author | Kim, Sang Heon | - |
dc.contributor.author | HAN, JEONG WOO | - |
dc.contributor.author | Ko, Young Gun | - |
dc.contributor.author | Chung, Eun Na | - |
dc.contributor.author | Kim, Soo Hyun | - |
dc.date.accessioned | 2021-11-20T02:50:11Z | - |
dc.date.available | 2021-11-20T02:50:11Z | - |
dc.date.created | 2021-11-19 | - |
dc.date.issued | 2007-07 | - |
dc.identifier.issn | 1662-9795 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/107515 | - |
dc.description.abstract | <jats:p>Porosity and pore size are needed for successful cell seeding and proliferation into porous scaffolds. This study was focused on a hydrogel-seeding method to improve cell adhesion and proliferation in tubular porous scaffolds for vascular grafts application. Tubular scaffolds were fabricated from a biodegradable elastic polymer, poly(L-lactide-co-ε-caprolactone) (PLCL) (50:50, Mn 1.58×105), by an extrusion-particulate leaching method. Vascular smooth muscle cells (VSMCs) were dispersed in collagen hydrogel and then seeded into the tubular PLCL scaffolds having various pore sizes, 50-100 μm, 100-200 μm, and 300-500 μm, respectively. As a result, the efficiency of cell adhesion and proliferation was dependent on the pore size of the scaffolds. Especially, the cell proliferation efficiency was improved by using the hydrogel-seeding method as compared with by using a previously established method. In summary, this study demonstrates that the efficiency of cell adhesion and proliferation was dependent on the pore size of the scaffolds in the hydrogel-seeding method.</jats:p> | - |
dc.language | English | - |
dc.publisher | Trans Tech Publications, Ltd. | - |
dc.relation.isPartOf | Key Engineering Materials | - |
dc.title | Optimization of Scaffold for a Successful Hydrogel-Seeding Method for Vascular Tissue Engineering | - |
dc.type | Article | - |
dc.identifier.doi | 10.4028/www.scientific.net/kem.342-343.333 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Key Engineering Materials, v.342-343, pp.333 - 336 | - |
dc.identifier.wosid | 000246657900084 | - |
dc.citation.endPage | 336 | - |
dc.citation.startPage | 333 | - |
dc.citation.title | Key Engineering Materials | - |
dc.citation.volume | 342-343 | - |
dc.contributor.affiliatedAuthor | HAN, JEONG WOO | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | Proceedings Paper | - |
dc.subject.keywordAuthor | hydrogel | - |
dc.subject.keywordAuthor | collagen | - |
dc.subject.keywordAuthor | smooth muscle cells | - |
dc.subject.keywordAuthor | vascular tissue engineering | - |
dc.subject.keywordAuthor | pore size | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Ceramics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Composites | - |
dc.description.journalRegisteredClass | scie | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
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