DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwang, DS | - |
dc.contributor.author | J. Herbert Waite | - |
dc.contributor.author | Matthew Tirrell | - |
dc.date.accessioned | 2016-04-01T02:45:30Z | - |
dc.date.available | 2016-04-01T02:45:30Z | - |
dc.date.created | 2010-11-03 | - |
dc.date.issued | 2010-02 | - |
dc.identifier.issn | 0142-9612 | - |
dc.identifier.other | 2010-OAK-0000021780 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/25712 | - |
dc.description.abstract | Many biological polyelectrolytes are capable of undergoing a fluid-fluid phase separation known as complex coacervation. Coacervates were prepared using hyaluronic acid (HA) and a recombinant fusion protein consisting of mussel adhesive motifs and the RGD peptide (fp-151-RGD). The low interfacial energy of the coacervate was exploited to coat titanium (Ti), a metal widely used in implant materials. The coacervate effectively distributed both HA and fp-151-RGD over the Ti surfaces and enhanced osteoblast proliferation. Approximately half of total fp-151-RGD and HA in the solution transferred to the titanium surface within 2 h. Titanium coated with coacervates having high residual negative surface charge showed the highest cell proliferation of preosteoblast cells (MC-3T3) compared to the treatments tested. Indeed, MC-3T3 cells on complex coacervate coated titanium foils exhibited over 5 times greater cell proliferation than bare, HA coated or fp-151-RGD coated titanium. (C) 2009 Elsevier Ltd. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | Elsevier B.V | - |
dc.relation.isPartOf | BIOMATERIALS | - |
dc.subject | Complex coacervate | - |
dc.subject | Hyaluronic acid | - |
dc.subject | Mussel adhesive protein | - |
dc.subject | fp-151-RGD | - |
dc.subject | MC-3T3 | - |
dc.subject | Biocoating | - |
dc.subject | CELL-ADHESION | - |
dc.subject | POLYELECTROLYTE MULTILAYERS | - |
dc.subject | RGD | - |
dc.subject | GROWTH | - |
dc.subject | CALIFORNICA | - |
dc.subject | CULTURE | - |
dc.title | Promotion of osteoblast proliferation on complex coacervation-based hyaluronic acid - recombinant mussel adhesive protein coatings on titanium | - |
dc.type | Article | - |
dc.contributor.college | 해양대학원 | - |
dc.identifier.doi | 10.1016/J.BIOMATERIALS.2009.10.041 | - |
dc.author.google | Hwang, DS | - |
dc.author.google | Waite, JH | - |
dc.author.google | Tirrell, M | - |
dc.relation.volume | 31 | - |
dc.relation.issue | 6 | - |
dc.relation.startpage | 1080 | - |
dc.relation.lastpage | 1084 | - |
dc.contributor.id | 10167197 | - |
dc.relation.journal | BIOMATERIALS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOMATERIALS, v.31, no.6, pp.1080 - 1084 | - |
dc.identifier.wosid | 000273985100007 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 1084 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1080 | - |
dc.citation.title | BIOMATERIALS | - |
dc.citation.volume | 31 | - |
dc.contributor.affiliatedAuthor | Hwang, DS | - |
dc.identifier.scopusid | 2-s2.0-72149121291 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 65 | - |
dc.description.scptc | 63 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CELL-ADHESION | - |
dc.subject.keywordPlus | POLYELECTROLYTE MULTILAYERS | - |
dc.subject.keywordPlus | RGD | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | CALIFORNICA | - |
dc.subject.keywordPlus | CULTURE | - |
dc.subject.keywordAuthor | Complex coacervate | - |
dc.subject.keywordAuthor | Hyaluronic acid | - |
dc.subject.keywordAuthor | Mussel adhesive protein | - |
dc.subject.keywordAuthor | fp-151-RGD | - |
dc.subject.keywordAuthor | MC-3T3 | - |
dc.subject.keywordAuthor | Biocoating | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
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