DC Field | Value | Language |
---|---|---|
dc.contributor.author | Junseok Lee, | - |
dc.contributor.author | Yeong Mi Lee | - |
dc.contributor.author | Jinhwan Kim | - |
dc.contributor.author | KIM, WON JONG | - |
dc.date.accessioned | 2018-05-04T02:35:59Z | - |
dc.date.available | 2018-05-04T02:35:59Z | - |
dc.date.created | 2018-03-05 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 2206-7418 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/41239 | - |
dc.description.abstract | It is widely known that the therapeutic effect of nanoparticle-based chemotherapeutics could be greatly enhanced by the introduction of the photodynamic effect. Herein we report a chlorin e6-incorporated mesoporous silica nanoparticles (MSNs) covered with a polyethylene glycol shell conjugated via a singlet oxygen-sensitive labile bis(alkylthio)alkene linker (CeAP-L-PEG). In this study, single irradiation with biocompatible red light induced both intracellular doxorubicin release and photochemical internalization, and consequently enhanced anti-cancer effect was observed in vitro and in vivo. This study suggests the potential of our precisely designed nanoparticle system for photodynamically assisted chemotherapy. | - |
dc.language | English | - |
dc.publisher | Ivyspring International Publisher | - |
dc.relation.isPartOf | NanoTheranostics | - |
dc.title | Doxorubicin/Ce6-Loaded Nanoparticle Coated with Polymer via Singlet Oxygen-Sensitive Linker for Photodynamically Assisted Chemotherapy | - |
dc.type | Article | - |
dc.identifier.doi | 10.7150/ntno.18576 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | NanoTheranostics, v.1, no.2, pp.196 - 207 | - |
dc.citation.endPage | 207 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 196 | - |
dc.citation.title | NanoTheranostics | - |
dc.citation.volume | 1 | - |
dc.contributor.affiliatedAuthor | KIM, WON JONG | - |
dc.identifier.scopusid | 2-s2.0-85034709607 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.type.docType | ARTICLE | - |
dc.description.journalRegisteredClass | scopus | - |
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